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Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barré syndromes.
Acta Neurol Belg. 1998 Dec; 98(4):322-6.AN

Abstract

Anti-GQ1b antibodies were assayed by an enzyme-linked immunosorbent assay in sera from patients with non-neurological disorders (N = 20), and with various neurological disorders (N = 59), including nine cases of Miller Fisher syndrome, 16 cases of Guillain-Barré syndrome and one case of acute post-infectious ophthalmoparesis. Such antibodies were found in most cases (8 out of 9) of Miller Fisher syndrome, and at very high titres, in one case of Guillain-Barré syndrome characterised by an initial ophthalmoparesis, and in the case of isolated post-infectious ophthalmoparesis. The latter was characterised by a long-lasting occurrence of these antibodies. Anti-GQ1b antibodies are specific for an immune-mediated neuropathy of the cranial, especially oculomotor, nerves.

Authors+Show Affiliations

Service de Neurologie, Cliniques Universitaires Saint-Luc, Bruxelles.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

9922819

Citation

Goffette, S, et al. "Clinical Relevance of the Determination of anti-GQ1b Antibodies in Miller Fisher and Guillain-Barré Syndromes." Acta Neurologica Belgica, vol. 98, no. 4, 1998, pp. 322-6.
Goffette S, Jeanjean A, Pierret F, et al. Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barré syndromes. Acta Neurol Belg. 1998;98(4):322-6.
Goffette, S., Jeanjean, A., Pierret, F., Peeters, A., & Sindic, C. J. (1998). Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barré syndromes. Acta Neurologica Belgica, 98(4), 322-6.
Goffette S, et al. Clinical Relevance of the Determination of anti-GQ1b Antibodies in Miller Fisher and Guillain-Barré Syndromes. Acta Neurol Belg. 1998;98(4):322-6. PubMed PMID: 9922819.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical relevance of the determination of anti-GQ1b antibodies in Miller Fisher and Guillain-Barré syndromes. AU - Goffette,S, AU - Jeanjean,A, AU - Pierret,F, AU - Peeters,A, AU - Sindic,C J, PY - 1999/1/29/pubmed PY - 1999/1/29/medline PY - 1999/1/29/entrez SP - 322 EP - 6 JF - Acta neurologica Belgica JO - Acta Neurol Belg VL - 98 IS - 4 N2 - Anti-GQ1b antibodies were assayed by an enzyme-linked immunosorbent assay in sera from patients with non-neurological disorders (N = 20), and with various neurological disorders (N = 59), including nine cases of Miller Fisher syndrome, 16 cases of Guillain-Barré syndrome and one case of acute post-infectious ophthalmoparesis. Such antibodies were found in most cases (8 out of 9) of Miller Fisher syndrome, and at very high titres, in one case of Guillain-Barré syndrome characterised by an initial ophthalmoparesis, and in the case of isolated post-infectious ophthalmoparesis. The latter was characterised by a long-lasting occurrence of these antibodies. Anti-GQ1b antibodies are specific for an immune-mediated neuropathy of the cranial, especially oculomotor, nerves. SN - 0300-9009 UR - https://www.unboundmedicine.com/medline/citation/9922819/Clinical_relevance_of_the_determination_of_anti_GQ1b_antibodies_in_Miller_Fisher_and_Guillain_Barré_syndromes_ L2 - https://medlineplus.gov/autoimmunediseases.html DB - PRIME DP - Unbound Medicine ER -