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Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa.
Antimicrob Agents Chemother. 1999 Feb; 43(2):415-7.AA

Abstract

Two new genes (mexXY) similar to mexAB, mexCD, and mexEF and mediating multidrug resistance were cloned from the chromosome of Pseudomonas aeruginosa. Elevated ethidium extrusion was observed with Escherichia coli cells harboring the plasmid carrying mexXY. This MexXY system confers higher resistance to fluoroquinolones than the MexAB and MexCD systems, and E. coli ToIC or P. aeruginosa OprM is necessary for the function of the MexXY system.

Authors+Show Affiliations

Department of Microbiology, Faculty of Pharmaceutical Sciences, Okayama, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9925549

Citation

Mine, T, et al. "Expression in Escherichia Coli of a New Multidrug Efflux Pump, MexXY, From Pseudomonas Aeruginosa." Antimicrobial Agents and Chemotherapy, vol. 43, no. 2, 1999, pp. 415-7.
Mine T, Morita Y, Kataoka A, et al. Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1999;43(2):415-7.
Mine, T., Morita, Y., Kataoka, A., Mizushima, T., & Tsuchiya, T. (1999). Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 43(2), 415-7.
Mine T, et al. Expression in Escherichia Coli of a New Multidrug Efflux Pump, MexXY, From Pseudomonas Aeruginosa. Antimicrob Agents Chemother. 1999;43(2):415-7. PubMed PMID: 9925549.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa. AU - Mine,T, AU - Morita,Y, AU - Kataoka,A, AU - Mizushima,T, AU - Tsuchiya,T, PY - 1999/1/30/pubmed PY - 1999/1/30/medline PY - 1999/1/30/entrez SP - 415 EP - 7 JF - Antimicrobial agents and chemotherapy JO - Antimicrob. Agents Chemother. VL - 43 IS - 2 N2 - Two new genes (mexXY) similar to mexAB, mexCD, and mexEF and mediating multidrug resistance were cloned from the chromosome of Pseudomonas aeruginosa. Elevated ethidium extrusion was observed with Escherichia coli cells harboring the plasmid carrying mexXY. This MexXY system confers higher resistance to fluoroquinolones than the MexAB and MexCD systems, and E. coli ToIC or P. aeruginosa OprM is necessary for the function of the MexXY system. SN - 0066-4804 UR - https://www.unboundmedicine.com/medline/citation/9925549/Expression_in_Escherichia_coli_of_a_new_multidrug_efflux_pump_MexXY_from_Pseudomonas_aeruginosa_ L2 - http://aac.asm.org/cgi/pmidlookup?view=long&pmid=9925549 DB - PRIME DP - Unbound Medicine ER -