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Percutaneous large-core biopsy of papillary breast lesions.
AJR Am J Roentgenol. 1999 Feb; 172(2):331-7.AA

Abstract

OBJECTIVE

This study was undertaken to assess the accuracy of percutaneous large-core biopsy in evaluating papillary breast lesions.

MATERIALS AND METHODS

A retrospective review of imaging-guided large-core breast biopsy of 1077 consecutive lesions revealed that papillary lesions were diagnosed in 34 (3%) cases. Surgical correlation (n = 22) or minimum 2 years' mammographic follow-up (n = 4) were available for 26 papillary lesions. Mammographic and histologic findings in these 26 cases were reviewed.

RESULTS

Percutaneous biopsy histology had benign findings in nine lesions, atypical in 10, and malignant in seven. Of seven lesions yielding benign papilloma at percutaneous biopsy, none (0%) had carcinoma at surgery or mammographic follow-up. Surgery revealed carcinoma in one of two lesions yielding papillomatosis at percutaneous biopsy. This lesion was a spiculated mass; surgical biopsy, recommended because of mammographic-histologic discordance, revealed a radial sclerosing lesion and ductal carcinoma in situ (DCIS). Of 10 papillary lesions with atypical ductal hyperplasia at percutaneous biopsy, surgery revealed DCIS in three (30%). Of seven lesions in which percutaneous biopsy yielded papillary DCIS, surgery revealed DCIS in all seven; three (43%) also had invasive carcinoma.

CONCLUSION

Among our patients, diagnosis by percutaneous core biopsy of benign papillary lesions proved to be accurate when concordant with imaging findings. Surgical excision was indicated when diagnosis by percutaneous biopsy revealed atypical papillary lesions or papillary DCIS. A larger series with longer follow-up is required to assess the clinical course of benign papillary lesions without atypia that are not excised after percutaneous large-core breast biopsy.

Authors+Show Affiliations

Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9930777

Citation

Liberman, L, et al. "Percutaneous Large-core Biopsy of Papillary Breast Lesions." AJR. American Journal of Roentgenology, vol. 172, no. 2, 1999, pp. 331-7.
Liberman L, Bracero N, Vuolo MA, et al. Percutaneous large-core biopsy of papillary breast lesions. AJR Am J Roentgenol. 1999;172(2):331-7.
Liberman, L., Bracero, N., Vuolo, M. A., Dershaw, D. D., Morris, E. A., Abramson, A. F., & Rosen, P. P. (1999). Percutaneous large-core biopsy of papillary breast lesions. AJR. American Journal of Roentgenology, 172(2), 331-7.
Liberman L, et al. Percutaneous Large-core Biopsy of Papillary Breast Lesions. AJR Am J Roentgenol. 1999;172(2):331-7. PubMed PMID: 9930777.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Percutaneous large-core biopsy of papillary breast lesions. AU - Liberman,L, AU - Bracero,N, AU - Vuolo,M A, AU - Dershaw,D D, AU - Morris,E A, AU - Abramson,A F, AU - Rosen,P P, PY - 1999/2/4/pubmed PY - 1999/2/4/medline PY - 1999/2/4/entrez SP - 331 EP - 7 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 172 IS - 2 N2 - OBJECTIVE: This study was undertaken to assess the accuracy of percutaneous large-core biopsy in evaluating papillary breast lesions. MATERIALS AND METHODS: A retrospective review of imaging-guided large-core breast biopsy of 1077 consecutive lesions revealed that papillary lesions were diagnosed in 34 (3%) cases. Surgical correlation (n = 22) or minimum 2 years' mammographic follow-up (n = 4) were available for 26 papillary lesions. Mammographic and histologic findings in these 26 cases were reviewed. RESULTS: Percutaneous biopsy histology had benign findings in nine lesions, atypical in 10, and malignant in seven. Of seven lesions yielding benign papilloma at percutaneous biopsy, none (0%) had carcinoma at surgery or mammographic follow-up. Surgery revealed carcinoma in one of two lesions yielding papillomatosis at percutaneous biopsy. This lesion was a spiculated mass; surgical biopsy, recommended because of mammographic-histologic discordance, revealed a radial sclerosing lesion and ductal carcinoma in situ (DCIS). Of 10 papillary lesions with atypical ductal hyperplasia at percutaneous biopsy, surgery revealed DCIS in three (30%). Of seven lesions in which percutaneous biopsy yielded papillary DCIS, surgery revealed DCIS in all seven; three (43%) also had invasive carcinoma. CONCLUSION: Among our patients, diagnosis by percutaneous core biopsy of benign papillary lesions proved to be accurate when concordant with imaging findings. Surgical excision was indicated when diagnosis by percutaneous biopsy revealed atypical papillary lesions or papillary DCIS. A larger series with longer follow-up is required to assess the clinical course of benign papillary lesions without atypia that are not excised after percutaneous large-core breast biopsy. SN - 0361-803X UR - https://www.unboundmedicine.com/medline/citation/9930777/Percutaneous_large_core_biopsy_of_papillary_breast_lesions_ L2 - https://www.ajronline.org/doi/10.2214/ajr.172.2.9930777 DB - PRIME DP - Unbound Medicine ER -