Tags

Type your tag names separated by a space and hit enter

[Modification of surgical strategy in HNPCC by molecular and clinical aspects].

Abstract

Because of the positive correlation between Amsterdam criteria and positive MSI analysis, a subtotal colectomy with ileorectal anastomosis seems to be indicated in patients with positive Amsterdam criteria to eliminate the high risk of metachronous colon cancer. In patients with an identified mutation in one of the known mismatch repair genes, a subtotal colectomy is indicated as well. In patients with positive Bethesda criteria, apart from the Amsterdam criteria, a subtotal colectomy seems only to be indicated if a positive MSI analysis is available.

Authors+Show Affiliations

Chirurgische Universitätsklinik Heidelberg.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

9931896

Citation

Wüllenweber, H P., et al. "[Modification of Surgical Strategy in HNPCC By Molecular and Clinical Aspects]." Langenbecks Archiv Fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft Fur Chirurgie. Kongress, vol. 115, 1998, pp. 1408-10.
Wüllenweber HP, Sutter C, Kadmon M, et al. [Modification of surgical strategy in HNPCC by molecular and clinical aspects]. Langenbecks Arch Chir Suppl Kongressbd. 1998;115:1408-10.
Wüllenweber, H. P., Sutter, C., Kadmon, M., Gebert, J., von Knebel-Doeberitz, M., & Herfarth, C. (1998). [Modification of surgical strategy in HNPCC by molecular and clinical aspects]. Langenbecks Archiv Fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft Fur Chirurgie. Kongress, 115, 1408-10.
Wüllenweber HP, et al. [Modification of Surgical Strategy in HNPCC By Molecular and Clinical Aspects]. Langenbecks Arch Chir Suppl Kongressbd. 1998;115:1408-10. PubMed PMID: 9931896.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Modification of surgical strategy in HNPCC by molecular and clinical aspects]. AU - Wüllenweber,H P, AU - Sutter,C, AU - Kadmon,M, AU - Gebert,J, AU - von Knebel-Doeberitz,M, AU - Herfarth,C, PY - 1999/2/5/pubmed PY - 1999/2/5/medline PY - 1999/2/5/entrez SP - 1408 EP - 10 JF - Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress JO - Langenbecks Arch Chir Suppl Kongressbd VL - 115 N2 - Because of the positive correlation between Amsterdam criteria and positive MSI analysis, a subtotal colectomy with ileorectal anastomosis seems to be indicated in patients with positive Amsterdam criteria to eliminate the high risk of metachronous colon cancer. In patients with an identified mutation in one of the known mismatch repair genes, a subtotal colectomy is indicated as well. In patients with positive Bethesda criteria, apart from the Amsterdam criteria, a subtotal colectomy seems only to be indicated if a positive MSI analysis is available. SN - 0942-2854 UR - https://www.unboundmedicine.com/medline/citation/9931896/[Modification_of_surgical_strategy_in_HNPCC_by_molecular_and_clinical_aspects]_ DB - PRIME DP - Unbound Medicine ER -