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Endoscopic sclerotherapy to arrest uncontrolled variceal bleeding in cirrhotic patients with high surgical risk.
Hepatogastroenterology. 1998 Nov-Dec; 45(24):2181-5.H

Abstract

BACKGROUND/AIMS

In 20-50% of patients bleeding from esophageal varices, conservative procedures fail to obtain hemostasis and prevent early recurrence.

METHODOLOGY

We retrospectively analyzed the efficacy and safety of endoscopic sclerotherapy in 66 cirrhotic patients with high surgical risk and persistence or recurrence of variceal bleeding in spite of adequate medical treatment (somatostatin and/or balloon tamponade).

RESULTS

Emergency sclerosis controlled bleeding in 46 out of 66 patients (70%). The remaining 20 patients underwent additional procedures to arrest the hemorrhage, and 6 died because of massive bleeding. Early rebleeding occurred in 5 patients (10%). The mortality within 2 days, 1 week, and 6 weeks was 9%, 17% and 32%, respectively. Death was attributed to hemorrhage in 9 cases. Sclerotherapy was associated with complications in 9 patients (14%).

CONCLUSION

These results suggest that emergency sclerotherapy is a safe and effective procedure in cirrhotic patients with high surgical risk and persistence or recurrence of bleeding after conservative hemostatic procedures.

Authors+Show Affiliations

Gastroenterology Department, Institut Clinic de Malalties Digestives, University of Barcelona, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

9951890

Citation

Llach, J, et al. "Endoscopic Sclerotherapy to Arrest Uncontrolled Variceal Bleeding in Cirrhotic Patients With High Surgical Risk." Hepato-gastroenterology, vol. 45, no. 24, 1998, pp. 2181-5.
Llach J, Bordas JM, Nieto I, et al. Endoscopic sclerotherapy to arrest uncontrolled variceal bleeding in cirrhotic patients with high surgical risk. Hepatogastroenterology. 1998;45(24):2181-5.
Llach, J., Bordas, J. M., Nieto, I., Landaeta, J., Elizalde, J. I., Mondelo, F., Gines, A., Salmeron, J. M., Mas, A., Teres, J., & Rodes, J. (1998). Endoscopic sclerotherapy to arrest uncontrolled variceal bleeding in cirrhotic patients with high surgical risk. Hepato-gastroenterology, 45(24), 2181-5.
Llach J, et al. Endoscopic Sclerotherapy to Arrest Uncontrolled Variceal Bleeding in Cirrhotic Patients With High Surgical Risk. Hepatogastroenterology. 1998 Nov-Dec;45(24):2181-5. PubMed PMID: 9951890.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic sclerotherapy to arrest uncontrolled variceal bleeding in cirrhotic patients with high surgical risk. AU - Llach,J, AU - Bordas,J M, AU - Nieto,I, AU - Landaeta,J, AU - Elizalde,J I, AU - Mondelo,F, AU - Gines,A, AU - Salmeron,J M, AU - Mas,A, AU - Teres,J, AU - Rodes,J, PY - 1999/2/10/pubmed PY - 1999/2/10/medline PY - 1999/2/10/entrez SP - 2181 EP - 5 JF - Hepato-gastroenterology JO - Hepatogastroenterology VL - 45 IS - 24 N2 - BACKGROUND/AIMS: In 20-50% of patients bleeding from esophageal varices, conservative procedures fail to obtain hemostasis and prevent early recurrence. METHODOLOGY: We retrospectively analyzed the efficacy and safety of endoscopic sclerotherapy in 66 cirrhotic patients with high surgical risk and persistence or recurrence of variceal bleeding in spite of adequate medical treatment (somatostatin and/or balloon tamponade). RESULTS: Emergency sclerosis controlled bleeding in 46 out of 66 patients (70%). The remaining 20 patients underwent additional procedures to arrest the hemorrhage, and 6 died because of massive bleeding. Early rebleeding occurred in 5 patients (10%). The mortality within 2 days, 1 week, and 6 weeks was 9%, 17% and 32%, respectively. Death was attributed to hemorrhage in 9 cases. Sclerotherapy was associated with complications in 9 patients (14%). CONCLUSION: These results suggest that emergency sclerotherapy is a safe and effective procedure in cirrhotic patients with high surgical risk and persistence or recurrence of bleeding after conservative hemostatic procedures. SN - 0172-6390 UR - https://www.unboundmedicine.com/medline/citation/9951890/Endoscopic_sclerotherapy_to_arrest_uncontrolled_variceal_bleeding_in_cirrhotic_patients_with_high_surgical_risk_ L2 - https://medlineplus.gov/cirrhosis.html DB - PRIME DP - Unbound Medicine ER -