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13,053 results
  • Incidence of new hepatitis C virus infection is still increasing in French MSM living with HIV. [Journal Article]
  • AIDSAIDS 2018 Feb 12
  • Pradat P, Huleux T, … Dat’AIDS study Group
  • CONCLUSIONS: Despite a high HCV treatment uptake and cure rate, the incidence of new HCV infection (first infection or reinfection) regularly increased in French HIV-positive MSM between 2012 and 2016. The incidence of reinfection fluctuated but remained constantly higher than the incidence of first infection, suggesting that a subgroup of MSM pursued high-risk practices following cure of a first infection.
  • Repeat testing of low-level HIV-1 RNA: assay performance and implementation in clinical trials. [Journal Article]
  • AIDSAIDS 2018 Feb 08
  • White K, Garner W, … Quirk E
  • CONCLUSIONS: The TaqMan HIV-1 RNA assay shows variability around 50 copies/ml that affects clinical trial results and may impact clinical practice. In participants with a history of viral load suppression, unexpected low-level viremia may be because of assay variability rather than low-drug adherence or true virologic failure. Retesting a stored aliquot of the same sample may differentiate between assay variability and virologic failure as the source of viremia. This retesting strategy could save time, money, and anxiety for patients and their providers, as well as decrease follow-up clinic visits without increasing the risk of virologic failure and resistance development.
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