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(Am J Respir Crit Care Med[TA])
14,751 results
  • Neonatal Pulmonary MRI of Bronchopulmonary Dysplasia Predicts Short-term Clinical Outcomes. [Journal Article]
  • AJAm J Respir Crit Care Med 2018 May 23
  • Higano NS, Spielberg DR, … Woods JC
  • CONCLUSIONS: Quiet-breathing neonatal pulmonary MRI can independently assess structural abnormalities of BPD, describe disease severity, and predict short-term outcomes more accurately than any individual standard clinical measure. Importantly, this non-ionizing technique can be implemented to phenotype disease and has potential to serially assess efficacy of individualized therapies.
  • Deterioration of Regional Lung Strain and Inflammation during Early Lung Injury. [Journal Article]
  • AJAm J Respir Crit Care Med 2018 May 22
  • Motta-Ribeiro GC, Hashimoto S, … Vidal Melo MF
  • CONCLUSIONS: Mechanical ventilation consistent with clinical practice did not generate excessive regional strain in heterogeneously aerated supine lungs. However, it allowed worsening of spatial strain distribution in these lungs, associated with increased inflammation. Our results support the implementation of early aeration homogenization in normal lungs.
  • Early Intravascular Events are Associated with Development of ARDS. [Journal Article]
  • AJAm J Respir Crit Care Med 2018 May 21
  • Abdulnour RE, Gunderson T, … Levy BD
  • CONCLUSIONS: Biomarkers of intravascular monocyte activation in at-risk patients were associated with development of ARDS. The potential clinical benefit of early aspirin for prevention of ARDS remains uncertain. Together, results of the biochemical and immunological analyses provide a window into the early pathogenesis of human ARDS, and represent potential vascular biomarkers of ARDS risk.
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