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(American Journal of Kidney Diseases[TA])
11,090 results
  • Patterns of Clinical Response to Eculizumab in Patients With C3 Glomerulopathy. [Journal Article]
  • AJAm J Kidney Dis 2018 Feb 08
  • Le Quintrec M, Lapeyraque AL, … Fakhouri F
  • CONCLUSIONS: Retrospective design without a control group, relatively small number of cases, inclusion of pediatric and adult cases.Eculizumab appears to be a potential treatment for patients with crescentic rapidly progressive C3 glomerulopathy. Its benefit in patients with non-rapidly progressing forms seems to be limited.
  • Pulmonary Hypertension, Mortality, and Cardiovascular Disease in CKD and ESRD Patients: A Systematic Review and Meta-analysis. [Journal Article]
  • AJAm J Kidney Dis 2018 Feb 08
  • Tang M, Batty JA, … Kalim S
  • CONCLUSIONS: Heterogeneity of included studies, possibility of residual confounding, unavailability of individual patient-level data, and possibility of outcome reporting bias.Pulmonary hypertension is associated with a substantially increased risk for death and cardiovascular events in patients with CKD and ESRD. Risk is higher in patients with ESRD receiving dialysis compared with patients with CKD stages 1 to 5. Understanding the effect of interventions to lower pulmonary artery pressure on the survival of these patents awaits their evaluation in randomized controlled trials.
  • Arteriovenous Fistula Maturation in Prevalent Hemodialysis Patients in the United States: A National Study. [Journal Article]
  • AJAm J Kidney Dis 2018 Feb 08
  • Woodside KJ, Bell S, … Saran R
  • CONCLUSIONS: This study relies on administrative data, with monthly recording of access use.We identified numerous associations between AVF maturation and patient-level factors in a recent national sample of US hemodialysis patients. After accounting for these patient factors, we observed substantial differences in AVF maturation across some ESRD networks, indicating a need for additional study of the provider, practice, and regional factors that explain AVF maturation.
  • Brain Magnetic Resonance Imaging Findings in Children and Young Adults With CKD. [Journal Article]
  • AJAm J Kidney Dis 2018 Feb 01
  • Hartung EA, Erus G, … Furth SL
  • CONCLUSIONS: Unable to assess changes in brain structure and kidney function over time; analysis limited to prespecified ROIs and neurocognitive domains.CKD in children and young adults may be associated with lower GM and higher WM volumes in some ROIs. Differences were relatively subtle in the CKD group as a whole, but were more prominent in recipients of a kidney transplant. However, neurocognitive performance was not explained by differences in brain ROI volumes, suggesting a functional rather than structural basis for neurocognitive impairment in CKD.
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