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(American Journal of Obstetrics Gynecology[TA])
39,917 results
  • Screening extremely obese pregnant women for obstructive sleep apnea. [Journal Article]
  • AJAm J Obstet Gynecol 2018 Sep 11
  • Dominguez JE, Grotegut CA, … Habib AS
  • CONCLUSIONS: We found that 24% of pregnant women with BMI greater than or equal to 40 kg.m-2 between 24 and 35 weeks gestation have OSA, defined as AHI > 5 events/hour on an overnight, type III home sleep apnea test. We found the Berlin questionnaire, American Society of Anesthesiologists checklist, STOP-BANG, OSA in pregnancy score by Facco et al., and the Epworth sleepiness scale were not useful screening tools for OSA in a cohort of obese pregnant women. However, age, BMI, neck circumference, frequent witnessed apneas and likely to fall asleep while driving were associated with OSA in this cohort and further studies are needed to adjust the criteria and thresholds within the available screening tools to better predict OSA in pregnant women with obesity.
  • Abruptio Placentae Risk and Genetic Variations in Mitochondrial Biogenesis and Oxidative Phosphorylation: Replication of a Candidate Gene Association Study. [Journal Article]
  • AJAm J Obstet Gynecol 2018 Sep 04
  • Workalemahu T, Enquobahrie DA, … Williams MA
  • CONCLUSIONS: In this study, we replicated previous findings and provide strong evidence for DNA variants encoding for genes involved in mitochondrial biogenesis and oxidative phosphorylation pathways, conferring risk for abruptio placentae. These results shed light on the mechanisms, implicating DNA variants encoding for proteins in mitochondrial function that are responsible for abruptio placentae risk. Therapeutic efforts to reduce risk of AP can be enhanced by improved biological understanding of maternal mitochondrial biogenesis/oxidative phosphorylation pathways as well as identification of women who would be at high risk for AP.
  • Inpatient opioid use after vaginal delivery. [Journal Article]
  • AJAm J Obstet Gynecol 2018 Aug 29
  • Badreldin N, Grobman WA, Yee LM
  • CONCLUSIONS: In a large cohort, nearly one-quarter of women use opioid analgesia during the last 24 hours of inpatient hospitalization following vaginal delivery. Although patient factors account for some of the variation in inpatient opioid use, both use of acetaminophen and having had postpartum orders written by an advanced practitioner were independently associated with lower odds of inpatient opioid use.
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