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(Ann Rheum Dis[TA])
16,813 results
  • HLA-B27, axial spondyloarthritis and survival. [Journal Article]
    Ann Rheum Dis. 2023 Sep 07 [Online ahead of print]Li Z, Khan MK, … Brown MA
  • CONCLUSIONS: AS patients, but not nr-axSpA patients, have a significantly shortened life expectancy. Increased mortality is particularly significant among women with HLA-B27-positive AS. HLA-B27 carriage in the European-ancestry general population does not influence survival, or the risk of death due to vascular disease.
  • Spanish cohort of VEXAS syndrome: clinical manifestations, outcome of treatments and novel evidences about UBA1 mosaicism. [Journal Article]
    Ann Rheum Dis. 2023 Sep 04 [Online ahead of print]Mascaro JM, Rodriguez-Pinto I, … Aróstegui JI
  • CONCLUSIONS: Thirty patients with adult-onset AID were definitively diagnosed with VEXAS syndrome through genetic analyses. Despite minor interindividual differences, their main characteristics were in concordance with previous reports. We detected for the first time the UBA1 mosaicism in non-haematopoietic tissue, which questions the previous concept of myeloid-restricted mosaicism and may have conceptual consequences for the disease mechanisms.
  • 2023 ACR/EULAR antiphospholipid syndrome classification criteria. [Journal Article]
    Ann Rheum Dis. 2023 Oct; 82(10):1258-1270.Barbhaiya M, Zuily S, … ACR/EULAR APS Classification Criteria Collaborators
  • CONCLUSIONS: These new ACR/EULAR APS classification criteria were developed using rigorous methodology with multidisciplinary international input. Hierarchically clustered, weighted, and risk-stratified criteria reflect the current thinking about APS, providing high specificity and a strong foundation for future APS research.
  • Contributions of joint damage-related events to gout pathogenesis: new insights from laboratory research. [Review]
    Ann Rheum Dis. 2023 Aug 16 [Online ahead of print]Xu H, Qin H, … Dalbeth N
  • Epidemiological and imaging findings indicate that gout frequently affects damaged joints. Recent studies suggest that the relationship between gout and joint damage may be more complex than a simple unidirectional link and that joint damage may promote the development of gout at affected sites. In this article, we review the clinical associations and recent laboratory research identifying events…
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