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(Arthritis Research Therapy[TA])
4,060 results
  • Methods for high-dimensonal analysis of cells dissociated from cyropreserved synovial tissue. [Journal Article]
  • ARArthritis Res Ther 2018 Jul 11; 20(1):139
  • Donlin LT, Rao DA, … Anolik JH
  • CONCLUSIONS: We have established a robust protocol to acquire viable cells from cryopreserved synovial tissue with intact transcriptomes and cell surface phenotypes. A centralized pipeline to generate multiple high-dimensional analyses of synovial tissue samples collected across a collaborative network was developed. Integrated analysis of such datasets from large patient cohorts may help define molecular heterogeneity within RA pathology and identify new therapeutic targets and biomarkers.
  • Radiographs in screening for sacroiliitis in children: what is the value? [Journal Article]
  • ARArthritis Res Ther 2018 Jul 11; 20(1):141
  • Weiss PF, Xiao R, … Chauvin NA
  • CONCLUSIONS: Interrater reliability of MRI was superior to radiographs for global sacroiliitis impression. Misclassification for both negative and positive radiographs was high across raters. Radiographs have limited utility in screening for sacroiliitis in children and result in a significant proportion of both false negative and positive findings versus MRI findings.
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