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52,064 results
  • The antitumor effects of entinostat in ovarian cancer require adaptive immunity. [Journal Article]
  • CCancer 2018 Nov 13
  • Smith HJ, McCaw TR, … Arend RC
  • CONCLUSIONS: In the current murine ovarian cancer model, entinostat treatment enhances beneficial immune responses. Moreover, these antitumor effects of entinostat are dependent on an intact immune system. Future studies combining entinostat with checkpoint inhibitors or other immunomodulatory agents may achieve more durable antitumor responses in patients with ovarian cancer.
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