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51,243 results
  • Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics. [Journal Article]
  • CCancer 2018 May 22
  • Cronin KA, Lake AJ, … Jemal A
  • CONCLUSIONS: For all cancer sites combined, cancer incidence rates decreased among men but were stable among women. Overall, there continue to be significant declines in cancer death rates among both men and women. Differences in rates and trends by race and ethnic group remain. Progress in reducing cancer mortality has not occurred for all sites. Examining stage distribution and 5-year survival by stage highlights the potential benefits associated with early detection and treatment. Cancer 2018. © 2018 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
  • The impact of pharmacokinetic gene profiles across human cancers. [Journal Article]
  • BCBMC Cancer 2018 May 21; 18(1):577
  • Zimmermann MT, Therneau TM, Kocher JA
  • CONCLUSIONS: While the resolution of clinical information within the dataset is not ideal, and modeling the relative contribution of each gene to the activity of each therapy remains a challenge, our approach demonstrates that somatic PK alterations should be integrated into the interpretation of somatic transcriptomic profiles as they likely have a significant impact on the survival of specific patients. We believe that this approach will aid the prospective design of personalized therapeutic strategies.
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