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Unbound Medicine.
(Climacteric[TA])
2,030 results
  • The treatment of menopausal symptoms by traditional Chinese medicine in Asian countries. [Journal Article]
    Climacteric. 2020 Oct 23 [Online ahead of print]Wang YP, Yu Q
  • Menopausal symptoms (or climacteric syndrome) refer to a series of symptoms that occur during the perimenopausal and early postmenopausal period. About 80% of women will have various degrees of menopausal symptoms, and most of them need associated treatment. Asian women are more inclined to choose traditional Chinese medicine (TCM) in terms of therapeutic method, and menopausal hormone therapy ha…
  • Compounded bioidentical menopausal hormone therapy - a physician perspective. [Journal Article]
    Climacteric. 2020 Oct 19 [Online ahead of print]Stuenkel CA
  • One of the defining moments of the 80-year evolution of menopausal hormone therapy (MHT) was the 2002 reveal of the initial results of the combined hormone therapy arm of the Women's Health Initiative (WHI) clinical trial. The exodus from regulatory approved MHT was prompt and profound and accompanied by a rapid acceleration of the compounding pharmacy 'bioidentical' hormone therapy industry. Com…
  • Vaginal lubricants and moisturizers: a review into use, efficacy, and safety. [Journal Article]
    Climacteric. 2020 Sep 29 [Online ahead of print]Potter N, Panay N
  • Vaginal dryness is common during and after menopause due to declining estrogen. It is one of the symptoms of vulvovaginal atrophy (VVA), which is part of the genitourinary syndrome of menopause. This can be distressing for women and cause pain, discomfort, and dyspareunia. Vaginal dryness affects over 50% of postmenopausal women but is under-reported and thus under-treated due to barriers to seek…
  • Celiac disease and bone health: is there a gap in the management of postmenopausal osteoporosis? [Journal Article]
    Climacteric. 2020 Sep 22 [Online ahead of print]Stuckey BGA, Mahoney LA, … Brown SJ
  • Malabsorption due to celiac disease (CD) may contribute to postmenopausal osteoporosis. This study aimed to survey participants with CD regarding their bone density, fractures, and bone-preserving medications; to compare tolerance of bone-preserving medications in participants with and without CD; and to review the evidence for CD screening and osteoporosis therapies in the setting of CD. We recr…
  • Premature ovarian insufficiency: an International Menopause Society White Paper. [Journal Article]
    Climacteric. 2020 10; 23(5):426-446.Panay N, Anderson RA, … Wolfman W
  • The aim of this International Menopause Society White Paper on premature ovarian insufficiency (POI) is to provide the latest information regarding this distressing condition. The impact of POI has far-reaching consequences due to its impact on general, psychological, and sexual quality of life, fertility prospects, and long-term bone, cardiovascular, and cognitive health. Progress in fully under…
  • Uterine bleeding with hormone therapies in menopausal women: a systematic review. [Journal Article]
    Climacteric. 2020 Sep 07 [Online ahead of print]Pickar JH, Archer DF, … Mirkin S
  • Uterine bleeding is a common reason why women discontinue menopausal hormone therapy (HT). This systematic review compared bleeding profiles reported in studies for continuous-combined HT approved in North America and Europe for moderate to severe vasomotor symptoms in postmenopausal women with a uterus. Non-head-to-head studies showed that uterine bleeding varies by formulation and administratio…
  • Lessons from KEEPS: the Kronos Early Estrogen Prevention Study. [Journal Article]
    Climacteric. 2020 Sep 03 [Online ahead of print]Miller VM, Taylor HS, … Harman SM
  • The Kronos Early Estrogen Prevention Study (KEEPS) was a randomized, double-blind, placebo-controlled trial designed to determine the effects of hormone treatments (menopausal hormone treatments [MHTs]) on the progression of carotid intima-medial thickness (CIMT) in recently menopausal women. Participants less than 3 years from menopause and without a history of overt cardiovascular disease (CVD)…
  • Insomnia and menopause: a narrative review on mechanisms and treatments. [Journal Article]
    Climacteric. 2020 Sep 03 [Online ahead of print]Proserpio P, Marra S, … Nappi RE
  • The menopausal transition is associated with an increased frequency of sleep disturbances. Insomnia represents one of the most reported symptoms by menopausal women. According to its pathogenetic model (3-P Model), different predisposing factors (i.e. a persistent condition of past insomnia and aging per se) increase the risk of insomnia during menopause. Moreover, multiple precipitating and perp…
  • Acupuncture for menopausal symptoms in Chinese women: a systematic review. [Journal Article]
    Climacteric. 2020 Jul 30 [Online ahead of print]Qin Y, Ruan X, … Hu X
  • Menopause-related symptoms are common problems of middle-aged women that can seriously affect their quality of life. Menopausal hormone therapy (MHT) for climacteric symptoms is the first choice recommended by the International Menopause Society and likewise by other societies and institutions covering this field. However, non-hormonal therapies can be an alternative effective option, especially …
  • Testosterone use in postmenopausal women. [Journal Article]
    Climacteric. 2020 Jul 24 [Online ahead of print]Martínez-García A, Davis SR
  • The physiological, clinical and therapeutic aspects of testosterone in women's health are still a matter of controversy and debate. Quality evidence data of clinical trials favors the use of transdermal testosterone in postmenopausal women with female sexual dysfunction causing distress. Doses of testosterone should approximate physiological testosterone levels found in premenopausal women, avoid…
  • Managing vasomotor symptoms effectively without hormones. [Journal Article]
    Climacteric. 2020 Jul 22 [Online ahead of print]McCormick CA, Brennan A, Hickey M
  • Vasomotor symptoms (hot flushes and/or night sweats) affect approximately 80% of women over the menopause transition and can affect quality of life, productivity, and relationships. Vasomotor symptoms are the main reason for seeking treatment during the menopausal transition. Although menopausal hormone therapy (MHT) is effective for symptom management, the majority of symptomatic women do not ta…
  • The use of hysteroscopy in endometrial cancer: old questions and novel challenges. [Journal Article]
    Climacteric. 2020 08; 23(4):330-335.Török P, Molnár S, … Jakab A
  • Endometrial cancer is the most common gynecological malignancy with a relatively good overall prognosis. It traditionally has two subtypes: type 1 (endometrioid carcinoma) and type 2 (non-endometrioid carcinoma). The prognosis is excellent for stage I endometrioid cancer, with a 5-year survival rate of 96%. However, the prognosis is much worse for women with high-risk endometrial cancer. Effectiv…
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