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(Clinical Evidence[TA])
1,543 results
  • Rheumatoid arthritis: previously untreated early disease. [Review]
  • BCBMJ Clin Evid 2016 Aug 01; 2016
  • Gunasekera WM, Kirwan JR
  • CONCLUSIONS: In this systematic overview, we categorised the efficacy for 22 comparisons based on information about the effectiveness and safety of bDMARDs (monotherapy or combined with csDMARDs), csDMARDs (monotherapy or combined with other csDMARDs), glucocorticoids combined with methotrexate or other csDMARDs, and methotrexate (monotherapy or combined with other csDMARDs), identifying interventions which were likely or unlikely to be beneficial.
  • Subarachnoid haemorrhage (spontaneous aneurysmal). [Review]
  • BCBMJ Clin Evid 2016 Mar 17; 2016
  • Sweeney K, Silver N, Javadpour M
  • CONCLUSIONS: In this systematic overview, we categorised the efficacy for one comparison based on information about the effectiveness and safety of endovascular coiling versus surgical clipping.
  • Malaria: fluid therapy in severe disease. [Review]
  • BCBMJ Clin Evid 2016 Jan 22; 2016
  • Hodgson SH, Angus BJ
  • CONCLUSIONS: In this systematic overview, we categorised the efficacy for three interventions based on information about the effectiveness and safety of human albumin, intravenous fluids, and whole blood or plasma.
  • MRSA: treating people with infection. [Review]
  • BCBMJ Clin Evid 2016 Feb 16; 2016
  • Rae N, Jarchow-MacDonald A, … Marwick CA
  • CONCLUSIONS: In this systematic overview we categorised the efficacy for five interventions, based on information about the effectiveness and safety of cephalosporins (ceftobiprole, ceftaroline), daptomycin, linezolid, quinupristin-dalfopristin, pristinamycin (streptogramins), and tigecycline.
  • Trachoma. [Review]
  • BCBMJ Clin Evid 2016 Feb 09; 2016
  • Lansingh VC
  • CONCLUSIONS: In this systematic overview, we categorised the efficacy for seven interventions based on information about the effectiveness and safety of antibiotics, face washing (alone or plus topical tetracycline), fly control (through the provision of pit latrines, and using insecticide alone or plus antibiotics), and health education.
  • Headache (chronic tension-type). [Review]
  • BCBMJ Clin Evid 2016 Feb 05; 2016
  • Ghadiri-Sani M, Silver N
  • CONCLUSIONS: In this systematic overview, we categorised the efficacy for 12 interventions based on information about the effectiveness and safety of non-drug treatments acupuncture and cognitive behavioural therapy (CBT), as well as the drug treatments amitriptyline, anticonvulsant drugs (sodium valproate, topiramate, or gabapentin), benzodiazepines, botulinum toxin, noradrenergic and specific serotonergic antidepressants (mirtazapine), NSAIDs (e.g. ibuprofen); opioid analgesics (e.g. codeine), paracetamol, serotonin re-uptake inhibitor antidepressants (SSRIs, SNRIs), and tricyclic antidepressants (other than amitriptyline).
  • Sickle cell disease. [Review]
  • BCBMJ Clin Evid 2016 Jan 22; 2016
  • Meremikwu MM, Okomo U
  • CONCLUSIONS: In this systematic overview, we categorised the efficacy for five interventions based on information about the effectiveness and safety of antibiotic prophylaxis in children aged under 5 years, antibiotic prophylaxis in children aged 5 years or older, hydroxyurea, malaria chemoprophylaxis, and pneumococcal vaccines.
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