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(Critical Care Medicine[TA])
21,661 results
  • Cecal Ligation and Puncture Alters Glucocorticoid Receptor Expression. [Journal Article]
  • CCCrit Care Med 2018 May 21
  • Abraham MN, Jimenez DM, … Deutschman CS
  • CONCLUSIONS: Cecal ligation and puncture altered glucocorticoid receptor α and glucocorticoid receptor β isoform expression in tissues and decreased functional responses in heart and liver. Decreases in glucocorticoid receptor α and increases in glucocorticoid receptor β might explain the diminished glucocorticoid responsiveness observed in sepsis.
  • Cooccurrence of Post-Intensive Care Syndrome Problems Among 406 Survivors of Critical Illness. [Journal Article]
  • CCCrit Care Med 2018 May 21
  • Marra A, Pandharipande PP, … Brummel NE
  • CONCLUSIONS: In this multicenter cohort study, one or more post-intensive care syndrome problems were present in the majority of survivors, but cooccurring problems were present in only one out of four. Education was protective from post-intensive care syndrome problems and frailty predictive of the development of post-intensive care syndrome problems. Future studies are needed to understand better the heterogeneous subtypes of post-intensive care syndrome and to identify modifiable risk factors.
  • Acute Neurologic Complications During Extracorporeal Membrane Oxygenation-A Systematic Review. [Journal Article]
  • CCCrit Care Med 2018 May 18
  • Sutter R, Tisljar K, Marsch S
  • CONCLUSIONS: Neurologic complications are reported frequently and with high occurrence rate, especially with venoarterial extracorporeal membrane oxygenation, and associated with high mortality calling for daily weaning from sedation and neuromuscular blockers for neurologic assessment and coagulation monitoring. The low quality of evidence indicates the need for higher quality studies in this context.
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