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(Curr Opin Mol Ther[TA])
923 results
  • Gene therapy: Have the risks associated with viral vectors been solved? [Editorial]
    Curr Opin Mol Ther 2010; 12(6):637-8Auman JT
  • Gene therapy has the potential to cure monogenic diseases through the replacement of the deleterious gene with a functional copy. While the field of gene therapy has been plagued by serious adverse events associated with therapy, it is hoped that new, safer viral vectors have reduced these risks greatly. However, recently published reports indicate that these new viral vectors are a potential ris…
  • Inflammation, stem cells and atherosclerosis genetics. [Review]
    Curr Opin Mol Ther 2010; 12(6):712-23Goldschmidt-Clermont PJ, Seo DM, … Velazquez OC
  • Atherosclerosis and its associated complications remain the primary cause of death in humans. Aging is the main contributor to atherosclerosis, compared with any other risk factor, yet the specific manner in which age increases risk (the 'aging-risk' mechanism) remains elusive. A novel concept for atherosclerosis risk implicates a lack of endothelial progenitor cell (EPC)-dependent arterial repai…
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