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(Current HIV research[TA])
865 results
  • The changes of positive selection within env gene of HIV-1 B', CRF07_BC and CRF08_BC from China over time. [Journal Article]
  • CHCurr HIV Res 2016 Dec 05
  • Li T, Sun B, … Yang R
  • CONCLUSIONS: The common positively selected sites identified in our study implied that they are important in viral survival and adaptation. Based on the role of V3 region in coreceptor determination and disease progression, our results suggested that the virulence of HIV-1 in China might be stable in the short time span. Given the overall increase tendency of positively selection sites in env, we might predict a less virulent state in the long run.
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