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(Diseases of the Colon and Rectum[TA])
11,040 results
  • A Variant of COL3A1 (rs3134646) Is Associated With Risk of Developing Diverticulosis in White Men. [Journal Article]
  • DCDis Colon Rectum 2018 Mar 12
  • Reichert MC, Kupcinskas J, … Lammert F
  • CONCLUSIONS: Because a candidate approach was used, additional relevant variants could be missed. Within our cohort of patients with diverticulosis, only a small proportion had diverticular disease and thus, we could not examine the variants in these subgroups. Functional studies, including the analysis of the involved collagens, are also warranted.Our study shows that a variant of COL3A1 (rs3134646) is associated with the risk of developing colonic diverticulosis in white men, whereas rs1800255 (COL3A1) and rs1800012 (COL1A1) were not associated with this condition after adjusting for confounding factors. Our data provide novel valuable insights in the genetic susceptibility to diverticulosis. See Video Abstract at
  • Increased Postoperative Morbidity Associated With Prolonged Laparoscopic Colorectal Resections Is Not Increased by Resident Involvement. [Journal Article]
  • DCDis Colon Rectum 2018 Mar 08
  • Kulaylat AS, Hollenbeak CS, Stewart DB
  • CONCLUSIONS: The study was limited by its retrospective design and inability to define the complexity of case and extent of resident involvement.Although longer operative times confer increased postoperative morbidity, there was no significant difference in complication rates within the highest tertile between cases with and without resident participation. Resident involvement does not appear to add to the risk of morbidity associated with longer and more complicated surgeries. See Video Abstract at
  • Closing Perianal Fistulas Using a Laser: Long-Term Results in 103 Patients. [Journal Article]
  • DCDis Colon Rectum 2018 Mar 08
  • Terzi MC, Agalar C, … Obuz F
  • CONCLUSIONS: This was a retrospective analysis of noncomparative data with a lack of formal prospective continence assessment.Closure of perianal fistulas using a laser should be considered as a treatment option but with modest expectations. Although our complete healing rate was not as high as in earlier studies, this technique is a reasonable option with nearly no risk of sphincter damage when treating perianal fistulas. See Video Abstract at
  • Recurrence of Rectal Prolapse After Surgical Repair in Women With Pelvic Organ Prolapse. [Journal Article]
  • DCDis Colon Rectum 2018 Mar 08
  • Catanzarite T, Klaristenfeld DD, … Alperin M
  • CONCLUSIONS: The retrospective design was a limitation of this study.Pelvic organ prolapse was associated with a higher rectal prolapse recurrence rate and earlier recurrence in women undergoing perineal, but not abdominal, repairs. Multidisciplinary evaluation can facilitate individualized management of women with rectal prolapse. Abdominal repair should be considered in women with concomitant rectal and pelvic organ prolapse. See Video Abstract, at
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