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(Diseases of the Colon and Rectum[TA])
11,195 results
  • Predictors of Metastases in Rectal Neuroendocrine Tumors: Results of a National Cohort Study. [Journal Article]
  • DCDis Colon Rectum 2018 Oct 11
  • Concors SJ, Sinnamon AJ, … Roses RE
  • CONCLUSIONS: This study was limited by its retrospective design.Tumor size and degree of differentiation are predictive of regional and distant metastatic disease in rectal neuroendocrine tumors. Patients with tumors >1.15 cm are at substantial risk of distant metastasis and should be staged and managed accordingly. See Video Abstract at
  • Evaluation of Healthcare Use and Clinical Outcomes of Alvimopan in Patients Undergoing Bowel Resection A Propensity Score-Matched Analysis. [Journal Article]
  • DCDis Colon Rectum 2018 Oct 11
  • Steele SR, Brady JT, … Delaney CP
  • CONCLUSIONS: The study was limited by its inability to generalize to the US population, because the database included a convenience sample of hospital discharges. The identification of patients undergoing bowel resection and their clinical conditions relied on the accuracy and completeness of International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis and procedure coding. There may be a confounding effect by the use of enhanced recovery pathways associated with the use of alvimopan.The use of alvimopan was associated with a reduction of 0.62 days in postsurgery length of stay and lower rates of postoperative GI complications, infections, and other in-hospital morbidities. See Video Abstract at
  • Impact of Disgust on Intentions to Undergo Colorectal Surgery. [Journal Article]
  • DCDis Colon Rectum 2018 Oct 11
  • Turner MC, O'Brien JD, … Ariely D
  • CONCLUSIONS: It is unknown whether these results will replicate with patients and the impact of competing emotions in clinical settings.Intentions to undergo colorectal surgery and recall of preoperative instructions are diminished in patients who experience disgust when presented with stoma information. Surgeons and care teams must account for this as they perform perioperative counseling to minimize interference with recall of important perioperative information. See Video Abstract at
  • Testing for Human Papillomavirus Strains 16 and 18 Helps Predict the Presence of Anal High-Grade Squamous Intraepithelial Lesions. [Journal Article]
  • DCDis Colon Rectum 2018 Oct 10
  • Sambursky JA, Terlizzi JP, Goldstone SE
  • CONCLUSIONS: This study was conducted in a single private practice specializing in anal dysplasia screening with a mostly male population, and results might not be generalizable.Testing of high-risk human papillomavirus strains 16/18 improves specificity and positive predictive value over cytology for anal dysplasia screening. Patients testing positive for strains 16/18 are at a high risk for high-grade squamous intraepithelial lesions and should undergo high-resolution anoscopy regardless of the cytology result. See Video Abstract at
  • Thoracic Epidural Analgesia: Does It Enhance Recovery? [Journal Article]
  • DCDis Colon Rectum 2018 Oct 10
  • Rosen DR, Wolfe RC, … Silviera ML
  • CONCLUSIONS: The retrospective observational design was a limitation of this study.The use of thoracic epidural analgesia within an enhanced recovery after surgery protocol was not found to be associated with a reduction in length of stay or morphine milligram equivalents consumed within the first 48 hours. We cannot recommend routine use of thoracic epidural analgesia within enhanced recovery after surgery protocols. See Video Abstract at
  • Predicting the Risk of Readmission From Dehydration After Ileostomy Formation: The Dehydration Readmission After Ileostomy Prediction Score. [Journal Article]
  • DCDis Colon Rectum 2018 Oct 09
  • Chen SY, Stem M, … Efron JE
  • CONCLUSIONS: Limitations of this study pertained to those of the American College of Surgeons National Surgical Quality Improvement Program, including a lack of generalizability, lack of ileostomy-specific variables, and inability to capture multiple readmission International Classification of Diseases, 9/10 edition, codes.The Dehydration Readmission After Ileostomy Prediction score is a validated scoring system that identifies patients at risk for dehydration readmission after ileostomy formation. It is a specific approach to optimize patient factors, implement interventions, and prevent readmissions. See Video Abstract at
  • Intra-abdominal Sepsis After Ileocolic Resection in Crohn's Disease: The Role of Combination Immunosuppression. [Journal Article]
  • DCDis Colon Rectum 2018 Oct 09
  • McKenna NP, Habermann EB, … Lightner AL
  • CONCLUSIONS: This study is limited by its single-institution tertiary referral center scope.Combination immunosuppression and previous intestinal resection were both associated with the development of intra-abdominal sepsis. In light of these results, surgeons should consider the effects of combination immunosuppression and a history of previous intestinal resection, in addition to other risk factors, when deciding which patients warrant temporary intestinal diversion. See Video Abstract at
  • What Is the Risk of Anal Carcinoma in Patients With Anal Intraepithelial Neoplasia III? [Journal Article]
  • DCDis Colon Rectum 2018 Oct 09
  • Lee GC, Kunitake H, … Ricciardi R
  • CONCLUSIONS: The registry did not record HIV status, surveillance schedule, use of high-resolution anoscopy, or provider specialty.In the largest published cohort of patients with anal intraepithelial neoplasia III, ≈10% of patients were projected to develop anal cancer within 5 years. Nearly one third of anal cancers were diagnosed at stage T2 or higher despite a previous diagnosis of anal intraepithelial neoplasia III. Ablative procedures were associated with a decreased risk of cancer. This study highlights the considerable rate of malignancy in patients with anal intraepithelial neoplasia III and the need for effective therapies and surveillance. See Video Abstract at
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