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(European journal of medical research[TA])
1,972 results
  • Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing. [Journal Article]
  • EJEur J Med Res 2018 Sep 28; 23(1):45
  • Braun SA, Baran J, … Gerber PA
  • CONCLUSIONS: Our data suggest that tumor cells are more susceptible to IM as compared to differentiated HEK. This is evident by a stronger IM-mediated induction of proinflammatory chemokines in tumor cells, which may result in a tumor cell-directed inflammatory response and rapid tumor destruction. In addition, IM induces AMP in keratinocytes and seems not to severely interfere with keratinocyte migration, which contributes to a fast and uncomplicated wound healing. Surprising is a selective inhibition of keratinocyte migration by IM at the concentration of 10-7 M pointing to very dose depending biological effects, induced by IM.
  • Evaluation of preoperative anxiety and fear of anesthesia using APAIS score. [Journal Article]
  • EJEur J Med Res 2018 Sep 11; 23(1):41
  • Celik F, Edipoglu IS
  • CONCLUSIONS: We think that being aware of the patients' anxiety and finding appropriate approaches for their anxieties can be valuable. APAIS is an effective method to measure patient anxiety and it might be beneficial to use during preoperative visits. Patient satisfaction and superior outcomes can be achieved in this way. Trial registration ISRCTN43960422. Registered 19/02/2018-Retrospectively registered. http://www.isrctn.com/ISRCTN43960422.
  • Vasomotion of mice mesenteric arteries during low oxygen levels. [Journal Article]
  • EJEur J Med Res 2018 Aug 25; 23(1):38
  • Westhoff J, Weismüller K, … Henrich M
  • CONCLUSIONS: The present study demonstrated that hypoxic vasodilatation in mice mesenteric arteries is mediated by a NO-independent mechanism. In this experimental setting, we found evidence for Ca2+-mediated activation of ion channels causing hypoxic vasodilatation.
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