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- No association of TP53 codon 72 and intron 3 16-bp duplication polymorphisms with breast cancer risk in Chinese Han women: new evidence from a population-based case-control investigation. [Journal Article]
- EJEur J Med Res 2018 Oct 11; 23(1):47
- CONCLUSIONS: The results suggested that the two TP53 polymorphisms did not affect breast cancer risk in Chinese Han women, but the heterozygous Arg/Pro may exist as the possible risk genotype of the codon 72 polymorphism in contrast to the homozygous Arg/Arg and Pro/Pro.
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- The Munich Ankle Questionnaire (MAQ): a self-assessment tool for a comprehensive evaluation of ankle disorders. [Journal Article]
- EJEur J Med Res 2018 Sep 28; 23(1):46
- CONCLUSIONS: The MAQ is a reliable and valid self-assessment measurement tool for the follow-up examination regarding subjective and objective parameters of traumatic and degenerative ankle pathologies. The MAQ has no limitation to specific disorders and allows a broad application.
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- Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing. [Journal Article]
- EJEur J Med Res 2018 Sep 28; 23(1):45
- CONCLUSIONS: Our data suggest that tumor cells are more susceptible to IM as compared to differentiated HEK. This is evident by a stronger IM-mediated induction of proinflammatory chemokines in tumor cells, which may result in a tumor cell-directed inflammatory response and rapid tumor destruction. In addition, IM induces AMP in keratinocytes and seems not to severely interfere with keratinocyte migration, which contributes to a fast and uncomplicated wound healing. Surprising is a selective inhibition of keratinocyte migration by IM at the concentration of 10-7 M pointing to very dose depending biological effects, induced by IM.
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- Prospective randomized controlled trial in the treatment of lateral epicondylitis with a new dynamic wrist orthosis. [Journal Article]
- EJEur J Med Res 2018 Sep 15; 23(1):43
- CONCLUSIONS: The elbow orthosis appears to accelerate the healing process with respect to the PRTEE and pain on the VAS (12 weeks follow-up), although there is an adjustment after 12 months in both groups and a significant improvement of symptoms is achieved in all endpoints.
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- Polymorphonuclear (PMN) elastase in patients after severe traumatic brain injury. [Journal Article]
- EJEur J Med Res 2018 Sep 15; 23(1):44
- CONCLUSIONS: This is the first study to demonstrate that the PMN elastase levels in CSF significantly increased in the early posttraumatic phase (48 h and 72 h after TBI) in patients. The function of the BCSFB showed no significant influence on the PMN levels.
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- Elbow arthroscopy in children and adolescents: analysis of outcome and complications. [Journal Article]
- EJEur J Med Res 2018 Sep 15; 23(1):42
- CONCLUSIONS: Elbow arthroscopy is an appropriate and safe treatment option in children and adolescents with good and excellent postoperative results.
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- A comparative study on the validity and reliability of anterior, medial, and posterior approaches for internal fixation in the repair of fractures of the coronoid process of the ulna. [Journal Article]
- EJEur J Med Res 2018 Sep 11; 23(1):40
- CONCLUSIONS: In summary, the approach used influences fracture healing or the outcome after osteosynthesis. The posterior internal fixation method produced satisfactory functional outcomes in patients with fractures of the coronoid process of the ulna.
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- Evaluation of preoperative anxiety and fear of anesthesia using APAIS score. [Journal Article]
- EJEur J Med Res 2018 Sep 11; 23(1):41
- CONCLUSIONS: We think that being aware of the patients' anxiety and finding appropriate approaches for their anxieties can be valuable. APAIS is an effective method to measure patient anxiety and it might be beneficial to use during preoperative visits. Patient satisfaction and superior outcomes can be achieved in this way. Trial registration ISRCTN43960422. Registered 19/02/2018-Retrospectively registered. http://www.isrctn.com/ISRCTN43960422.
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- Biomechanical and histological analyses of the fracture healing process after direct or prolonged reduction. [Journal Article]
- EJEur J Med Res 2018 Sep 04; 23(1):39
- CONCLUSIONS: A single reduction maneuver has a beneficial effect in the early phase of the fracture healing process compared to repeated reduction maneuvers. In the later phase of fracture healing, no differences were found between the groups.
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- Vasomotion of mice mesenteric arteries during low oxygen levels. [Journal Article]
- EJEur J Med Res 2018 Aug 25; 23(1):38
- CONCLUSIONS: The present study demonstrated that hypoxic vasodilatation in mice mesenteric arteries is mediated by a NO-independent mechanism. In this experimental setting, we found evidence for Ca2+-mediated activation of ion channels causing hypoxic vasodilatation.
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