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- Memory and attention during an alcohol hangover. [Journal Article]
- HPHum Psychopharmacol 2019; 34(4):e2701
- CONCLUSIONS: Selective attention was significantly impaired during alcohol hangover. The differences between the hangover and control group did not reach significance for other forms of attention or memory.
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- Thyroid structure and function in long-term lithium-treated and lithium-naïve bipolar patients. [Journal Article]
- HPHum Psychopharmacol 2019; 34(4):e2708
- CONCLUSIONS: The results show a significant association between long-term lithium treatment and the increase of TSH and fT4, the decrease of fT3, higher thyroid volume, and more frequent goiter and nodular goiter. The effect of lithium on thyroid structure was not associated with its effect on thyroid hormones.
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- Association of blood cell counts with the risk of olanzapine- or clozapine-induced dyslipidemia in Chinese schizophrenia patients. [Journal Article]
- HPHum Psychopharmacol 2019; 34(4):e2699
- CONCLUSIONS: The profile of peripheral blood cells may be an early biomarker for predicting the risk of metabolic disorders and cardiovascular diseases in schizophrenia patients treated with SGAs.
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- Effect of acute modafinil ingestion on cognitive and physical performance following mental exertion. [Journal Article]
- HPHum Psychopharmacol 2019; 34(4):e2700
- CONCLUSIONS: Operationally, modafinil may offer advantages given the established longer half-life than other psychostimulants, despite the variable response. The impact of higher heart rates and disrupted sleep on performance must also be considered.
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- Effect of antidepressant treatment on plasma levels of neuroinflammation-associated molecules in patients with somatic symptom disorder with predominant pain around the orofacial region. [Journal Article]
- HPHum Psychopharmacol 2019; 34(4):e2698
- CONCLUSIONS: Inflammatory mechanisms may be involved in the pathophysiology and/or treatment response of somatic symptom disorders with predominant pain around the orofacial region.
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- The effects of GSK2981710, a medium-chain triglyceride, on cognitive function in healthy older participants: A randomised, placebo-controlled study. [Journal Article]
- HPHum Psychopharmacol 2019; 34(3):e2694
- CONCLUSIONS: Over a duration of 14 days, increasing plasma BHB levels with daily administration of GSK2981710 had no effects on neuronal activity or cognitive function. This result indicates that modulating plasma ketone levels with GSK2981710 may be ineffective in improving cognitive function in healthy older adults, or the lack of observed effect could be related to several factors including study population, plasma BHB concentrations, MCT composition, or treatment duration.
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- Exploring characteristics associated with first benzodiazepine prescription in patients with affective disorders and related diagnoses. [Journal Article]
- HPHum Psychopharmacol 2019; 34(3):e2695
- CONCLUSIONS: Patients with affective disorders frequently received BZDs as first prescription with significant differences between and within mood and anxiety disorders.
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- Low- and high-dose aripiprazole augmentation and plasma levels of homovanillic acid in major depressive disorder: A randomized, open-label study. [Journal Article]
- HPHum Psychopharmacol 2019; 34(3):e2696
- CONCLUSIONS: Increasing aripiprazole from the early period appeared useful for immediate response, although caution is needed when increasing the dose >6 mg/day. pHVA may be a possible indicator of the response to aripiprazole augmentation. Caution is needed in interpreting these findings because of the small sample size.
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- Factors influencing lithium pharmacokinetics in patients with acute mania: A population pharmacokinetic analysis. [Journal Article]
- HPHum Psychopharmacol 2019; 34(3):e2697
- CONCLUSIONS: A population pharmacokinetic model of lithium with good performance was developed in Thai patients with acute mania. This model can be used to assist clinicians in individualized lithium therapy.
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- Effects of olanzapine during cognitive and emotional processing in schizophrenia: A review of functional magnetic resonance imaging findings. [Review]
- HPHum Psychopharmacol 2019; 34(3):e2693
- CONCLUSIONS: The results of the reviewed studies suggest that in patients with schizophrenia, olanzapine treatment might lead to a more physiological brain activity coupled with regulation of dopamine release. Future studies should further corroborate these hypotheses using larger samples and homogeneous experimental tasks.
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