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(JAMA : Journal of the American Medical Association[TA])
72,021 results
  • Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. [Journal Article]
  • JAMAJAMA 2018 Dec 11; 320(22):2354-2364
  • Choi SH, Weng LC, … DiscovEHR study and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
  • CONCLUSIONS: In a case-control study, there was a statistically significant association between an LOF variant in the TTN gene and early-onset AF, with the variant present in a small percentage of participants with early-onset AF (the case group). Further research is necessary to understand whether this is a causal relationship.
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