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(Journal of Allergy and Clinical Immunology[TA])
17,364 results
  • Health Disparities among Children with Asthma in the U.S. by Place of Residence. [Journal Article]
  • JAJ Allergy Clin Immunol Pract 2018 May 18
  • Sullivan PW, Ghushchyan V, … Ortiz B
  • CONCLUSIONS: Poor-urban residence may be independently associated with asthma control and treatment even after controlling for individual characteristics like race and ethnicity. Future research is needed to understand the sources of these geographic health disparities in order to more successfully target public health interventions.
  • Autoinflammatory mutation in NLRC4 reveals an LRR-LRR oligomerization interface. [Journal Article]
  • JAJ Allergy Clin Immunol 2018 May 17
  • Moghaddas F, Zeng P, … Masters SL
  • CONCLUSIONS: This is the first report of a mutation in the LRR domain of NLRC4 causing autoinflammatory disease. c.G1965C/p.W655C NLRC4 increased inflammasome activation in vitro. Data generated from various NLRC4 mutations provides evidence that the LRR-LRR interface has an important, previously unrecognized role in oligomerization of the NLRC4 inflammasome complex.
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