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(Journal of Clinical Pathology[TA])
16,106 results
  • CDK12: an emerging therapeutic target for cancer. [Journal Article]
  • JCJ Clin Pathol 2018 Aug 13
  • Lui GYL, Grandori C, Kemp CJ
  • Cyclin-dependent kinase 12 (CDK12) belongs to the cyclin-dependent kinase (CDK) family of serine/threonine protein kinases that regulate transcriptional and post-transcriptional processes, thereby mo...
  • p16. [Journal Article]
  • JCJ Clin Pathol 2018 Aug 03
  • Serra S, Chetty R
  • The p16 gene belongs to INK4 family of genes and is made up of four members: p16 INK4A , p15 INK4B , p18 INK4C and p19 INK4D , all of which share biological properties, namely, inhibition of c...
  • Review of diagnostic error in anatomical pathology and the role and value of second opinions in error prevention. [Journal Article]
  • JCJ Clin Pathol 2018 Aug 01
  • Peck M, Moffatt D, … Badrick T
  • CONCLUSIONS: It was possible to ascertain that gynaecology, dermatopathology and gastrointestinal specimens had presented the greatest diagnostic challenge to the participant pathologists, determined as highest rate of diagnostic inaccuracy, that is, major discordance with respective case target diagnoses.Through a combination of routine second opinions, directed retrospective peer review and participation in appropriate external quality assurance schemes, the risk associated with these diagnoses can be minimised.
  • Results of the UK NEQAS for Molecular Genetics reference sample analysis. [Journal Article]
  • JCJ Clin Pathol 2018 Jul 20
  • Richman SD, Fairley J, … Deans ZC
  • CONCLUSIONS: Over 100 laboratories took the opportunity to test the 'educational reference sample', showing a willingness to further validate their testing platforms. While it was encouraging to see that the most widely reported variants were those which should be included in routine testing panels, reporting of variants was potentially open to interpretation, thus clarity is still required on whether laboratories selectively reported variants, by either clinical relevance or variant frequency.
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