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(Journal of Psychiatry and Neuroscience[TA])
1,357 results
  • Lifetime major depression and grey-matter volume [Journal Article]
  • JPJ Psychiatry Neurosci 2018 Sep 18; 43(6)
  • Ancelin ML, Isabelle C, … Isabelle C
  • CONCLUSIONS: Major depressive disorder was associated with persistent volume reductions in the deep nuclei and insula and with enlargements in visual cortex subregions; alterations varied according to age of onset and genotype.
  • White matter network alterations in patients with depersonalization/derealization disorder. [Journal Article]
  • JPJ Psychiatry Neurosci 2018; 43(5):347-357
  • Sierk A, Daniels JK, … Walter H
  • CONCLUSIONS: To ensure ecological validity, patients with certain comorbidities or psychotropic medication were included in the study. Confirmatory replications are necessary to corroborate the results of this explorative investigation.In patients with DPD, the structural connectivity between brain regions crucial for multimodal integration and emotion regulation may be altered. Aberrations in fibre tract communication seem to be not solely a secondary effect of local grey matter volume loss, but may present a primary pathophysiology in patients with DPD.
  • Resting-state functional connectivity in individuals with bipolar disorder during clinical remission: a systematic review. [Journal Article]
  • JPJ Psychiatry Neurosci 2018; 43(5):298-316
  • Syan SK, Smith M, … Minuzzi L
  • CONCLUSIONS: We found heterogeneity in the analysis methods used.Stability of the DMN, FPN and SN may reflect a state of remission. Further, DMN hypoconnectivity may reflect a positive history of psychosis in patients with bipolar disorder compared with controls, highlighting a potentially different neural phenotype of psychosis in people with bipolar disorder. Resting-state functional connectivity changes between the amygdala, prefrontal cortex and cingulate cortex may reflect a neural correlate of subthreshold symptoms experienced in bipolar disorder euthymia, the trait-based pathophysiology of bipolar disorder and/or a compensatory mechanism to maintain a state of euthymia.
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