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(Journal of Psychiatry and Neuroscience[TA])
1,335 results
  • White matter network alterations in patients with depersonalization/derealization disorder. [Journal Article]
  • JPJ Psychiatry Neurosci 2018 Jun 06; 43(4):170110
  • Sierk A, Daniels JK, … Walter H
  • CONCLUSIONS: To ensure ecological validity, patients with certain comorbidities or psychotropic medication were included in the study. Confirmatory replications are necessary to corroborate the results of this explorative investigation.In patients with DPD, the structural connectivity between brain regions crucial for multimodal integration and emotion regulation may be altered. Aberrations in fibre tract communication seem to be not solely a secondary effect of local grey matter volume loss, but may present a primary pathophysiology in patients with DPD.
  • The maternal brain in women with a history of early-life maltreatment: an imagination-based fMRI study of conflictual versus pleasant interactions with children. [Journal Article]
  • JPJ Psychiatry Neurosci 2018 May 16; 43(4):170026
  • Neukel C, Bertsch K, … Herpertz SC
  • CONCLUSIONS: Region-of-interest analyses, which were performed in addition to whole-brain analyses, were exploratory in nature, because they were not further controlled for multiple comparisons.Results suggest that for mothers with early-life maltreatment, conflictual interactions with their child may be more salient and behaviourally relevant than pleasant interactions, and that their salience network is poorly modulated by the brain regions involved in mentalizing processes. This activation pattern offers new insights into the mechanisms behind the intergenerational effects of maltreatment and into options for reducing these effects.
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