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(Journal of Psychiatry and Neuroscience[TA])
1,372 results
  • Lateral orbitofrontal dysfunction in the Sapap3 knockout mouse model of obsessive–compulsive disorder [Journal Article]
  • JPJ Psychiatry Neurosci 2018 11 07; 44(1)
  • Lei H, Lai J, … Feng G
  • CONCLUSIONS: We provide, to our knowledge, the first direct in vivo electrophysiological evidence of detailed functional alterations in different neuronal types in the lateral OFC of an OCD mouse model. These findings may help in understanding the underlying neuropathophysiology and circuitry mechanisms for phenotypes relevant to OCD, and may help generate and refine hypotheses about potential biomarkers for further investigation.
  • Performance monitoring and post-error adjustments in adults with attention-deficit/hyperactivity disorder: an EEG analysis [Journal Article]
  • JPJ Psychiatry Neurosci 2018 11 01; 43(6):396-406
  • Ehlis ACE, Deppermann SD, Fallgatter AJF
  • CONCLUSIONS: Based on previous reports of post-error behavioural alterations in childhood samples, we conclude that people with ADHD develop compensatory strategies across the lifespan that lead to inconspicuous post-error behaviour in adulthood. Neurophysiologically, however, subtle alterations remain, indicating a perseverance of at least some frontal lobe deficits in people with ADHD who are partially medicated, particularly with respect to action-monitoring and post-error adaptation.
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