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(Journal of Toxicology Clinical toxicology[TA])
1,738 results
  • Methamphetamine toxicity secondary to intravaginal body stuffing. [Case Reports]
  • JTJ Toxicol Clin Toxicol 2004; 42(7):987-9
  • Kashani J, Ruha AM
  • CONCLUSIONS: We report an unusual case of intravaginal body stuffing that lead to severe methamphetamine toxicity in a young woman. This case highlights the potential for severe methamphetamine poisoning secondary to intravaginal stuffing. If either body packing or stuffing is suspected, a vaginal exam may be warranted.
  • Do adenosine receptors play a role in amitriptyline-induced cardiovascular toxicity in rats? [Journal Article]
  • JTJ Toxicol Clin Toxicol 2004; 42(7):945-54
  • Kalkan S, Aygoren O, … Tuncok Y
  • CONCLUSIONS: Adenosine antagonists were found to be effective in improving hypotension, QRS prolongation and survival time in our rat model of amitriptyline toxicity. Additionally, amitriptyline-induced cardiotoxicity was abolished by pretreatment with adenosine receptor antagonists. These results suggest that adenosine receptors may have a role in the pathophysiology of amitriptyline-induced cardiovascular toxicity. Adenosine A1 and A2a receptor antagonists may be promising agents for reversing amitriptyline-induced cardiovascular toxicity.
  • Position paper: gastric lavage. [Review]
  • JTJ Toxicol Clin Toxicol 2004; 42(7):933-43
  • Vale JA, Kulig K, … European Association of Poisons Centres and Clinical Toxicologists
  • Gastric lavage should not be employed routinely, if ever, in the management of poisoned patients. In experimental studies, the amount of marker removed by gastric lavage was highly variable and dimin...
  • Acute endosulfan poisoning with cerebral edema and cardiac failure. [Case Reports]
  • JTJ Toxicol Clin Toxicol 2004; 42(6):927-32
  • Eyer F, Felgenhauer N, … Zilker TR
  • CONCLUSIONS: Endosulfan is a highly toxic organochlorine insecticide that produces well-known neurological symptoms of tonic-clonic convulsions, headache, dizziness and ataxia but also can cause gastrointestinal symptoms and metabolic disturbances. Life-threatening cerebral edema and hemodynamic instability may occur. Treatment is symptomatic and supportive.
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