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(Nature Reviews Cancer[TA])
1,912 results
  • Using immunotherapy to boost the abscopal effect. [Review]
  • NRNat Rev Cancer 2018 Feb 16
  • Ngwa W, Irabor OC, … Formenti SC
  • More than 60 years ago, the effect whereby radiotherapy at one site may lead to regression of metastatic cancer at distant sites that are not irradiated was described and called the abscopal effect (...
  • Genetic insights into the morass of metastatic heterogeneity. [Review]
  • NRNat Rev Cancer 2018 Feb 09
  • Hunter KW, Amin R, … Wakefield L
  • Tumour heterogeneity poses a substantial problem for the clinical management of cancer. Somatic evolution of the cancer genome results in genetically distinct subclones in the primary tumour with dif...
  • Targeting minimal residual disease: a path to cure? [Review]
  • NRNat Rev Cancer 2018 Jan 29
  • Luskin MR, Murakami MA, … Weinstock DM
  • Therapeutics that block kinases, transcriptional modifiers, immune checkpoints and other biological vulnerabilities are transforming cancer treatment. As a result, many patients achieve dramatic resp...
  • Fanconi anaemia and cancer: an intricate relationship. [Review]
  • NRNat Rev Cancer 2018; 18(3):168-185
  • Nalepa G, Clapp DW
  • Fanconi anaemia (FA) is a genetic disorder that is characterized by bone marrow failure (BMF), developmental abnormalities and predisposition to cancer. Together with other proteins involved in DNA r...
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