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775 results
  • Neural Substrates of Depression and Resilience. [Review]
  • NNeurotherapeutics 2017 Apr 10
  • Han MH, Nestler EJ
  • There is an urgent need for more effective medications to treat major depressive disorder, as fewer than half of depressed patients achieve full remission and many are not responsive with currently a...
  • Tumor Vaccines for Malignant Gliomas. [Review]
  • NNeurotherapeutics 2017; 14(2):345-357
  • Srinivasan VM, Ferguson SD, … Heimberger AB
  • Despite continued research efforts, glioblastoma multiforme (GBM) remains the deadliest brain tumor. Immunotherapy offers a novel way to treat this disease, the genetic signature of which is not comp...
  • Cancer of the Peripheral Nerve in Neurofibromatosis Type 1. [Review]
  • NNeurotherapeutics 2017; 14(2):298-306
  • Staedtke V, Bai RY, Blakeley JO
  • The RASopathy neurofibromatosis 1 is an autosomal dominant hereditary cancer syndrome that represents a major risk for the development of malignancies, particularly malignant peripheral nerve sheath ...
  • Reward Circuitry in Addiction. [Review]
  • NNeurotherapeutics 2017 Mar 21
  • Cooper S, Robison AJ, Mazei-Robison MS
  • Understanding the brain circuitry that underlies reward is critical to improve treatment for many common health issues, including obesity, depression, and addiction. Here we focus on insights into th...
  • Therapeutic Hypothesis Testing With Rodent Brain Tumor Models. [Review]
  • NNeurotherapeutics 2017; 14(2):385-392
  • Wainwright DA, Horbinski CM, … James CD
  • The development and application of rodent models for preclinical testing of novel therapeutics and approaches for treating brain tumors has been a mainstay of neuro-oncology preclinical research for ...
  • Convection-Enhanced Delivery. [Review]
  • NNeurotherapeutics 2017; 14(2):358-371
  • Mehta AM, Sonabend AM, Bruce JN
  • Convection-enhanced delivery (CED) is a promising technique that generates a pressure gradient at the tip of an infusion catheter to deliver therapeutics directly through the interstitial spaces of t...
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