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Unbound Medicine.
(Psychol Med[TA])
8,664 results
  • Attentional bias toward negative stimuli in PTSD: an eye-tracking study. [Journal Article]
    Psychol Med. 2022 Oct 19 [Online ahead of print]Veerapa E, Grandgenevre P, … D'Hondt F
  • CONCLUSIONS: PTSD is associated with an AB toward negative stimuli, characterized by heightened sustained attention toward negative scenes once detected. This study sheds light on the dynamics of AB to negative stimuli in PTSD and encourages us to consider optimized therapeutic interventions targeting abnormal AB patterns.
  • Disordered gambling in a longitudinal birth cohort: from childhood precursors to adult life outcomes. [Journal Article]
    Psychol Med. 2022 Oct 18 [Online ahead of print]Slutske WS, Richmond-Rakerd LS, … Caspi A
  • CONCLUSIONS: Socioeconomic, financial, and legal outcomes in adulthood are not merely consequences of disordered gambling, but also are predicted from childhood precursors. Deflecting the trajectories of young people at risk for developing disordered gambling may help to ameliorate not just the development of later disordered gambling, but also other associated adverse outcomes.
  • Mismatch negativity and clinical trajectories in psychotic disorders: Five-year stability and predictive utility. [Journal Article]
    Psychol Med. 2022 Oct 13 [Online ahead of print]Donaldson KR, Jonas K, … Kotov R
  • CONCLUSIONS: These results imply that MMN measures a neural deficit that is reasonably stable up to five years. Results support disordered cognition and negative symptoms as preceding reduced MMN, which then may operate as a mechanism driving reductions in everyday functioning and the worsening of auditory hallucinations in chronic psychotic disorders. This pattern may inform models of illness course, clarifying the relationships amongst biological mechanisms of predictive processing and clinical deficits in chronic psychosis and allowing us to better understand the mechanisms driving such impairments over time.
  • Non-affective psychotic disorders and risk of dementia: a systematic review and meta-analysis. [Review]
    Psychol Med. 2022 Oct 06 [Online ahead of print]Miniawi SE, Orgeta V, Stafford J
  • Non-affective psychotic disorders have been associated with an increased risk of developing dementia. However, research in this area remains limited, highlighting the need for an up-to-date systematic review and meta-analysis of the evidence. We aimed to systematically review and quantify the risk of dementia associated with psychotic disorders. We searched four electronic databases for longitudi…
  • Subcortical structures associated with childhood trauma and perceived stress in schizophrenia. [Journal Article]
    Psychol Med. 2022 Sep 26 [Online ahead of print]Fan F, Tan S, … Tan Y
  • CONCLUSIONS: Patients with schizophrenia had more exposure to early-life trauma and poorer stress coping. Both childhood trauma and perceived stress were associated with smaller amygdala volumes. The relationship between early-life trauma and perceived stress was mediated by right amygdala GMV in patients with schizophrenia. These findings together suggest the long-term effects of childhood trauma on perceived stress and the subcortical volumetric correlates of the effects in schizophrenia.
  • Variables influencing conditioning-evoked hallucinations: overview and future applications. [Review]
    Psychol Med. 2022 Sep 23 [Online ahead of print]Fry BR, Roberts D, … Johnson AW
  • Hallucinations occur in the absence of sensory stimulation and result in vivid perceptual experiences of nonexistent events that manifest across a range of sensory modalities. Approaches from the field of experimental and cognitive psychology have leveraged the idea that associative learning experiences can evoke conditioning-induced hallucinations in both animals and humans. In this review, we d…
  • Exposure to psychotropic medications and mortality in schizophrenia: a 5-year national cohort study. [Journal Article]
    Psychol Med. 2022 Sep 22 [Online ahead of print]Lin JY, Yeh LL, Pan YJ
  • CONCLUSIONS: The results indicate that in the treatment of schizophrenia, antipsychotics and antidepressants are associated with lower mortality when using adequate dosages and mood stabilizers and sedative-hypnotics with higher mortality compared with no use. Furthermore, exposure to sedative-hypnotics is associated with a dose-related increased mortality risk which warrants clinical attention and further study.
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