- Attentional bias toward negative stimuli in PTSD: an eye-tracking study. [Journal Article]Psychol Med. 2022 Oct 19 [Online ahead of print]PM
- CONCLUSIONS: PTSD is associated with an AB toward negative stimuli, characterized by heightened sustained attention toward negative scenes once detected. This study sheds light on the dynamics of AB to negative stimuli in PTSD and encourages us to consider optimized therapeutic interventions targeting abnormal AB patterns.
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- Cortical gyrification differences between early- and late-onset obsessive-compulsive disorder: neurobiological evidence for neurodevelopmentally distinct subtypes. [Journal Article]Psychol Med. 2022 Oct 19 [Online ahead of print]PM
- CONCLUSIONS: Our findings provide a neurobiological marker to distinguish the OCD population into more neurodevelopmentally homogeneous subtypes, which may contribute to the understanding of the neurodevelopmental underpinnings of an etiology in early-onset OCD consistent with the accumulated phenotypic evidence of greater neurodevelopmental deficits in early-onset OCD than in late-onset OCD.
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- Is good science leading the way in the therapeutic use of psychedelic drugs? [Journal Article]Psychol Med. 2022 Oct 19 [Online ahead of print]PM
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- Moving toward precision PTSD treatment: predicting veterans' intensive PTSD treatment response using continuously updating machine learning models. [Journal Article]Psychol Med. 2022 Oct 19 [Online ahead of print]PM
- CONCLUSIONS: Utilizing continuously updating models in PTSD treatments may be beneficial for clinicians in determining whether an individual is responding, and when this determination can be made.
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- Utility of PHQ-2, PHQ-8 and PHQ-9 for detecting major depression in primary health care: a validation study in Spain. [Journal Article]Psychol Med. 2022 Oct 19 [Online ahead of print]PM
- CONCLUSIONS: PHQ is a good and valuable tool for detecting major depression in PHC patients in Spain.
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- Disordered gambling in a longitudinal birth cohort: from childhood precursors to adult life outcomes. [Journal Article]Psychol Med. 2022 Oct 18 [Online ahead of print]PM
- CONCLUSIONS: Socioeconomic, financial, and legal outcomes in adulthood are not merely consequences of disordered gambling, but also are predicted from childhood precursors. Deflecting the trajectories of young people at risk for developing disordered gambling may help to ameliorate not just the development of later disordered gambling, but also other associated adverse outcomes.
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- A systematic review and meta-analysis of the evidence on inflammation in depressive illness and symptoms in chronic and end-stage kidney disease. [Journal Article]Psychol Med. 2022 Oct 18 [Online ahead of print]PM
- CONCLUSIONS: We found evidence for an association of higher levels of pro-inflammatory and lower anti-inflammatory cytokines and DS in patients with CKD/ESKF. Clinical trials are needed to investigate whether anti-inflammatory therapies will be effective in the prevention and treatment of DS in these patients with multiple comorbidities.
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- Mismatch negativity and clinical trajectories in psychotic disorders: Five-year stability and predictive utility. [Journal Article]Psychol Med. 2022 Oct 13 [Online ahead of print]PM
- CONCLUSIONS: These results imply that MMN measures a neural deficit that is reasonably stable up to five years. Results support disordered cognition and negative symptoms as preceding reduced MMN, which then may operate as a mechanism driving reductions in everyday functioning and the worsening of auditory hallucinations in chronic psychotic disorders. This pattern may inform models of illness course, clarifying the relationships amongst biological mechanisms of predictive processing and clinical deficits in chronic psychosis and allowing us to better understand the mechanisms driving such impairments over time.
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- Deviations from a typical development of the cerebellum in youth are associated with psychopathology, executive functions and educational outcomes. [Journal Article]Psychol Med. 2022 Oct 13 [Online ahead of print]PM
- CONCLUSIONS: Deviations in the cerebellar typical development are associated with outcomes in youth that have long-lasting consequences. This study highlights both the potential of typical developing models and the important role of the cerebellum in mental health, cognition and education.
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- Clinical and psychological factors associated with resilience in patients with schizophrenia: data from the Italian network for research on psychoses using machine learning. [Journal Article]Psychol Med. 2022 Oct 11 [Online ahead of print]PM
- CONCLUSIONS: We identified an accurate, meaningful and generalizable clinical-psychological signature associated with resilience in SCZ. This study delivers relevant information regarding psychological and clinical factors that non-pharmacological interventions could target in schizophrenia.
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- Non-affective psychotic disorders and risk of dementia: a systematic review and meta-analysis. [Review]Psychol Med. 2022 Oct 06 [Online ahead of print]PM
- Non-affective psychotic disorders have been associated with an increased risk of developing dementia. However, research in this area remains limited, highlighting the need for an up-to-date systematic review and meta-analysis of the evidence. We aimed to systematically review and quantify the risk of dementia associated with psychotic disorders. We searched four electronic databases for longitudi…
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- Neurological and psychiatric disorders among autistic adults: a population healthcare record study. [Journal Article]Psychol Med. 2022 Oct 03 [Online ahead of print]PM
- CONCLUSIONS: We found that a range of psychiatric conditions were more frequently recorded in autistic individuals. We add to understanding of under-reporting and diagnostic overshadowing in autism. With increasing awareness of autism, services should be cognisant of the psychiatric conditions that frequently co-occur in this population.
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- Psychotic experiences and negative symptoms from adolescence to emerging adulthood: developmental trajectories and associations with polygenic scores and childhood characteristics. [Journal Article]Psychol Med. 2022 Oct 03 [Online ahead of print]PM
- CONCLUSIONS: Our results suggest latent heterogeneity in the development of paranoia, hallucinations, and negative symptoms in young people that is associated with specific polygenic scores and childhood characteristics.
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- Associations Between Depression and Cardiometabolic Health: A 27-Year Longitudinal Study - Corrigendum. [Journal Article]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
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- Connectome-based prediction of eating disorder-associated symptomatology. [Journal Article]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
- CONCLUSIONS: These findings point to the feasibility of using the functional connectome to predict ED symptomatology in the general population and provide the first evidence that functional interplay among distributed networks predicts body shape/weight concerns.
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- Using machine learning with intensive longitudinal data to predict depression and suicidal ideation among medical interns over time. [Journal Article]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
- CONCLUSIONS: Simpler ML methods may outperform more complex methods until passive-sensing features become better specified. For intensive longitudinal studies, there may be limited predictive value in collecting data for more than 2 months.
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- Internet use and psychological wellbeing among older adults in England: a difference-in-differences analysis over the COVID-19 pandemic. [Journal Article]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
- CONCLUSIONS: Besides enabling access to digital services, efforts to ensure older adults continue to be engaged members of an increasingly digital society could deliver returns in terms of a buffer against psychological distress.
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- Understanding the development of bipolar disorder and borderline personality disorder in young people: a meta-review of systematic reviews. [Review]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
- CONCLUSIONS: Prospective studies are required to increase our understanding of the development of BD and BPD onset and their complex interplay by concurrently examining multiple measures in BD and BPD at-risk populations.
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- Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes. [Journal Article]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
- CONCLUSIONS: These findings illustrate that the genetic associations between consumption and problem alcohol phenotypes and PTSD differ in both strength and direction. Thus, the genetic factors that may lead someone to develop PTSD and high levels of alcohol consumption are not the same as those that lead someone to develop PTSD and alcohol-related problems. Discussion around needing improved methods to better estimate heritabilities and genetic correlations in diverse and admixed ancestry samples is provided.
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- Gender differences in psychosocial function and self-reported health status in late-diagnosed autistic adults: results from the FACE-ASD national cohort. [Journal Article]Psychol Med. 2022 Sep 30 [Online ahead of print]PM
- CONCLUSIONS: To improve objective and subjective aspects of health outcome, gender differences and a wide range of co-occurring health conditions should be taken into account when designing healthcare provision for autistic adults.
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- Effects of psychosis-associated genetic markers on brain volumetry: a systematic review of replicated findings and an independent validation. [Review]Psychol Med. 2022 Sep 28 [Online ahead of print]PM
- CONCLUSIONS: Most literature findings were not herein replicated. Nevertheless, high degree/likelihood of replication was found for two genome-wide association studies- and one candidate-implicated SNPs, supporting their involvement in psychosis and brain structure.
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- Modulation of resting-state functional connectivity in default mode network is associated with the long-term treatment outcome in major depressive disorder. [Journal Article]Psychol Med. 2022 Sep 27 [Online ahead of print]PM
- CONCLUSIONS: Our findings demonstrated that the intrinsic DMN connectivity could be a unique and important target for treatment and recurrence prevention in MDD.
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- The neuropsychiatric aftermath of exposure to weapons of mass destruction: applying historical lessons to protect health during the war in Ukraine. [Journal Article]Psychol Med. 2022 Sep 26 [Online ahead of print]PM
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- Effectiveness of enhancing contact model on reducing family caregiving burden and improving psychological wellbeing among caregivers of persons with schizophrenia in rural China. [Journal Article]Psychol Med. 2022 Sep 26 [Online ahead of print]PM
- CONCLUSIONS: This is the first study to explore the effectiveness of ECM on reducing family caregiving burden and improving hope and QOL in rural China. The results indicate the ECM intervention, a comprehensive and multifaceted intervention, is more effective than the PFI in various aspects of mental wellbeing among FCPWS. Future research needs to confirm ECM's effectiveness in various population.
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- A longitudinal analysis of conspiracy beliefs and Covid-19 health responses. [Journal Article]Psychol Med. 2022 Sep 26 [Online ahead of print]PM
- CONCLUSIONS: The results provide stronger support for the hypothesis that conspiracy beliefs predict health responses over time than for the hypothesis that health responses predict conspiracy beliefs over time.
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- Subcortical structures associated with childhood trauma and perceived stress in schizophrenia. [Journal Article]Psychol Med. 2022 Sep 26 [Online ahead of print]PM
- CONCLUSIONS: Patients with schizophrenia had more exposure to early-life trauma and poorer stress coping. Both childhood trauma and perceived stress were associated with smaller amygdala volumes. The relationship between early-life trauma and perceived stress was mediated by right amygdala GMV in patients with schizophrenia. These findings together suggest the long-term effects of childhood trauma on perceived stress and the subcortical volumetric correlates of the effects in schizophrenia.
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- Prediction of impending mood episode recurrence using real-time digital phenotypes in major depression and bipolar disorders in South Korea: a prospective nationwide cohort study. [Journal Article]Psychol Med. 2022 Sep 23 [Online ahead of print]PM
- CONCLUSIONS: We predicted the onset of mood episode recurrences exclusively using digital phenotypes. Specifically, phenotypes indicating CR misalignment contributed the most to the prediction of episodes recurrences. Our findings suggest that monitoring of CR using digital devices can be useful in preventing and treating mood disorders.
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- Variables influencing conditioning-evoked hallucinations: overview and future applications. [Review]Psychol Med. 2022 Sep 23 [Online ahead of print]PM
- Hallucinations occur in the absence of sensory stimulation and result in vivid perceptual experiences of nonexistent events that manifest across a range of sensory modalities. Approaches from the field of experimental and cognitive psychology have leveraged the idea that associative learning experiences can evoke conditioning-induced hallucinations in both animals and humans. In this review, we d…
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- Exposure to psychotropic medications and mortality in schizophrenia: a 5-year national cohort study. [Journal Article]Psychol Med. 2022 Sep 22 [Online ahead of print]PM
- CONCLUSIONS: The results indicate that in the treatment of schizophrenia, antipsychotics and antidepressants are associated with lower mortality when using adequate dosages and mood stabilizers and sedative-hypnotics with higher mortality compared with no use. Furthermore, exposure to sedative-hypnotics is associated with a dose-related increased mortality risk which warrants clinical attention and further study.
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- Associations of negative affective biases and depressive symptoms in a community-based sample. [Journal Article]Psychol Med. 2022 Sep 21 [Online ahead of print]PM
- CONCLUSIONS: This suggests the presence of subtle negative affective biases at the level of emotion/condition in association with depressive symptoms across the sample, over and above those accounted for by non-affective cognition, with no evidence for affective biases in remitted individuals.
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