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(front med china[TA])
121 results
  • Natural history of HIV infection in former plasma donors in rural China. [Journal Article]
    Front Med China. 2010 Sep; 4(3):346-50.Zhang M, Shang H, … Hu QH
  • Patients infected through commercial blood-selling practices (former plasma donors, FPDs) in China represent a unique patient population compared to individuals infected through sexual contact or intravenous drug use. FPDs all have an approximate time of human immunodeficiency virus (HIV) infection during the mid-1990s. Few studies about the natural history of HIV infection in these patients were…
  • Autoimmune regulator regulates autophagy in THP-1 human monocytes. [Journal Article]
    Front Med China. 2010 Sep; 4(3):336-41.Shi L, Hu LH, Li YR
  • The autoimmune regulator (AIRE) is a crucial factor for the induction of central tolerance, and mutations in this gene lead to abnormal immune responses. However, the role of AIRE in autophagy in immune cells, especially in monocytes, is obscure. In the present study, we found that overexpression of AIRE in THP-1 human monocytes resulted in increased endogenous light chain 3 (LC3)-II level and el…
  • Effects of resistin on skeletal glucose metabolism. [Journal Article]
    Front Med China. 2010 Sep; 4(3):329-35.Li FP, Li ZZ, … Fu ZZ
  • Resistin is an adipokine highly related to insulin resistance (IR). The purpose of our research was to investigate how resistin influences skeletal glucose metabolism and explore its mechanisms. We constructed the recombinant plasmid pcDNA3.1 expressing resistin and then transfected it into C2C12 myocytes. The expression of resistin in C2C12 myocytes was detected by Western blotting. Glucose upta…
  • Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60. [Journal Article]
    Front Med China. 2010 Sep; 4(3):323-8.Wang L, Zhao S, … Zou P
  • This study explored the effects of nuclear factor-kappa B (NF-κB) inhibitor Bay 11-7082 on Fas/FasL system and Fas-mediated apoptosis in cell line HL-60 cells. The mRNA and protein levels of Fas, FasL, and X-linked inhibitor of apoptosis protein (XIAP) were detected by reverse transcription-polymerase chain reaction (RT-PCR) and flow cytometry (FCM); the level of sFasL was evaluated by enzyme-lin…
  • Early diagnosis and therapeutic choice of Klebsiella pneumoniae liver abscess. [Journal Article]
    Front Med China. 2010 Sep; 4(3):308-16.Li J, Fu Y, … Jiang W
  • Nowadays, pyogenic liver abscess (PLA) is still a common and severe intra-abdominal infection, and Klebsiella pneumoniae had emerged as the most common pathogenic bacteria worldwide in the past ten years. Our study aims to achieve an early pathogenic diagnosis and rational therapy modality for Klebsiella pneumoniae liver abscess (KLA) through clinical data analysis. A total of 197 inpatients in Z…
  • High-intensity focused ultrasound tumor ablation: review of ten years of clinical experience. [Review]
    Front Med China. 2010 Sep; 4(3):294-302.Zhang L, Wang ZB
  • High-intensity focused ultrasound (HIFU) is a technique to destroy tissue at depth within the body, selectively and without harming overlying and adjacent structures within the path of the beam because the ultrasonic intensity at the beam focus is much higher than that outside of the focus. Diagnostic ultrasound is the first imaging modality used for guiding HIFU ablation. In 1997, a patient with…
  • How to judge the association of postmenopausal hormone therapy and the risk of breast cancer. [Review]
    Front Med China. 2010 Sep; 4(3):290-3.Xu L
  • The relevance of postmenopausal hormone therapy (HT) for breast cancer risk has been long debated, although it is one of the most important barriers for women to accept HT. Various opinions have been reported from recent randomized clinical trials and epidemiological studies. These unanswered questions include: whether HT has a positive impact on breast cancer; whether risks of therapy with unopp…
  • Family planning technical services in China. [Review]
    Front Med China. 2010 Sep; 4(3):285-9.Wu SC
  • Family planning is a basic state policy in China. Its aim is to control population growth and to enhance population quality. Technical services are the key measures for implementing the family planning policy. In order to ensure that people use safe, effective, and appropriate contraceptive methods based on the government's commitment, China has established countrywide family planning service net…
  • Polycystic ovary syndrome. [Review]
    Front Med China. 2010 Sep; 4(3):280-4.Chen ZJ, Shi Y
  • Polycystic ovary syndrome (PCOS) is a common gynecologic endocrinopathy. The pathogenesis of PCOS is associated with both heredity and environment. PCOS has adverse impacts on female endocrine, reproduction, and metabolism. PCOS can impact women's reproductive health, leading to anovulatory infertility and higher rate of early pregnancy loss. PCOS has additional metabolic derangements, such as in…
  • Pathogenesis, diagnosis, and treatment of recurrent spontaneous abortion with immune type. [Review]
    Front Med China. 2010 Sep; 4(3):275-9.Lin QD, Qiu LH
  • Recurrent spontaneous abortion (RSA), defined as three or more consecutive pregnancy losses before 20 weeks of gestation, is difficult to treat in the clinical setting. It affects 1%-5% of women of reproductive age. In the investigations of immunopathogenesis, diagnosis, and treatment of RSA since the late 1980s, it was found that RSA was associated with abnormal maternal local or systemic immune…
  • Current situation and development of prenatal diagnosis in China. [Review]
    Front Med China. 2010 Sep; 4(3):271-4.Bian XM, Guo Q, Qi QW
  • Prenatal screening and diagnosis are major methods for control of birth defects, which is a very important problem in China. Here, we review current situation and development of prenatal screening and diagnosis in mainland China, including prenatal screening and prenatal diagnosis of fetal chromosome abnormalities, non-invasive prenatal diagnostic techniques and prenatal diagnosis of monogenic di…
  • Clinical significance of human papilloma virus infection in the cervical lesions. [Review]
    Front Med China. 2010 Sep; 4(3):264-70.Li S, Meng YH, … Ma D
  • Cervical lesions have been regarded as the common and frequently occurring diseases in China. Recently, the morbidity and youth tendency of cervical cancer have gradually increased. Cervical cancer, related with human papilloma virus (HPV) infection, has been one of the severest diseases threatening health and life of women, and is an infectious disease. The universality of HPV infection in the r…
  • HPV prevalence and genotyping in the cervix of Chinese women. [Review]
    Front Med China. 2010 Sep; 4(3):259-63.Wang SM, Li J, Qiao YL
  • The role of human papillomavirus (HPV) as an etiologic factor of cervical cancer has been firmly established, and prophylactic vaccines are now available and have been approved in many countries. Vaccination implies a promising future for cervical cancer prevention especially for countries with very limited access to screening. However, the vaccines are not accessible in mainland China at the mom…
  • Toll-like receptors in innate immunity and infectious diseases. [Review]
    Front Med China. 2010 Dec; 4(4):385-93.Wu MH, Zhang P, Huang X
  • The protective ability of host defense system is largely dependent on germ-line encoded pattern-recognition receptors (PRRs). These PRRs respond to a variety of exogenous pathogens or endogenous danger signals, by recognizing some highly conserved structures such as pathogen-associated molecular patterns (PAMPs) and danger/damage associated molecular patterns (DAMPs). The most studied PRRs are To…
  • Graft versus host disease after liver transplantation: a case report. [Case Reports]
    Front Med China. 2010 Dec; 4(4):469-72.Gao PJ, Leng XS, … Zhu JY
  • In documenting clinical experience in the diagnosis and treatment of graft versus host disease (GVHD), we retrospectively analyzed data of one case that has developed GVHD after liver transplantation. This patient exhibited fever, skin rash, and diarrhea on day 9 after liver transplantation. His liver function was normal. Skin biopsy showed scattered keratinocytes accompanied by satellite-like ly…
  • Diagnosis and management against the complications of human cystic echinococcosis. [Review]
    Front Med China. 2010 Dec; 4(4):394-8.Wen H, Aji T, Shao YM
  • Cystic echinococcosis (CE) (hydatidosis, hydatid disease) is a zoonosis caused by the larval stage of Echinococcus granulosus, typically affecting the liver. Hepatic cystic echinococcosis (HCE) is often asymptomatic, and symptoms occur largely when complications develop. Up to one-third of HCE can be shown their complications such as rupture of the cyst, secondary infection, and anaphylactic reac…
  • Molecular pathogenesis of acute myeloid leukemia: a diverse disease with new perspectives. [Review]
    Front Med China. 2010 Dec; 4(4):356-62.Thol F, Ganser A
  • Acute myeloid leukemia (AML) is a very heterogeneous neoplasm of the hematopoietic stem cell. Despite important achievements in the treatment of AML, the long term survival of patients with the disease remains poor. Understanding the pathogenesis of AML better is crucial for finding new treatment approaches. During AML development, hematopoietic precursor cells undergo clonal transformation in a …
  • Hilar cholangiocarcinoma: pathology and tumor biology. [Review]
    Front Med China. 2010 Dec; 4(4):371-7.Kuang D, Wang GP
  • Hilar cholangiocarcinoma, first described by Klatskin in 1965, is a relatively rare tumor arising from the bile ducts. The histomorphological features of hilar cholangiocarcinoma are identical with other extra- and intra-hepatic bile duct carcinomas. The most common disease associated with cholangiocarcinoma is primary sclerosing cholangitis. The development of cholangiocarcinoma is a multistep p…
  • The value of epigenetic markers in esophageal cancer. [Review]
    Front Med China. 2010 Dec; 4(4):378-84.Zhang XM, Guo MZ
  • Developing esophageal cancer is a multi-step process that begins with the accumulation of genetic and epigenetic alterations, and leads to the activation of oncogenes and the inactivation or loss of tumor suppressor genes (TSG). In addition to genetic alteration, epigenetic modifications, and in particular DNA methylation, are recognized as a common molecular alteration in human tumors. In esopha…
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