Relationship between Parkinson disease with dementia and dementia with Lewy bodies.
Parkinsonism Relat Disord. 2005 Aug; 11(5):305-9.PR

Abstract

Parkinson disease (PD) and dementia with Lewy bodies (DLB) are considered Lewy body diseases (LBDs). To clarify the relation between PD with dementia (PDD) and DLB, 30 patients with LBD were divided into pathological subtypes according to the consensus guidelines for DLB. Patients with PDD showed neocortical and limbic type of LBD as well as patients with DLB. Dementia had not been noted in 2 patients with neocortical type. Our results indicate that PDD and DLB share a common pathological substrate and that the pathological subtypes of LBD show considerable overlap in clinical manifestations.

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Authors+Show Affiliations

Guo L
Department of Neurology, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.
Itaya M
No affiliation info available
Takanashi M
No affiliation info available
Mizuno Y
No affiliation info available
Mori H
No affiliation info available

MeSH

Age of OnsetAgedAged, 80 and overDiagnosis, DifferentialFemaleHumansLewy Body DiseaseLimbic SystemMaleMiddle AgedNeocortexParkinson Disease

Pub Type(s)

Journal Article

Language

eng

PubMed ID

15882957