Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit.
J Clin Microbiol. 2008 Jun; 46(6):2099-101.JC

Abstract

We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region.

Links

Publisher Full Text
ncbi.nlm.nih.gov
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Authors+Show Affiliations

Zárate MS
Laboratorio de Bacteriología, Micología y Parasitología, Sección de Nefrología, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno CEMIC, Ciudad Autónoma de Buenos Aires, Argentina. sole_z@hotmail.com
Gales AC
No affiliation info available
Picão RC
No affiliation info available
Pujol GS
No affiliation info available
Lanza A
No affiliation info available
Smayevsky J
No affiliation info available

MeSH

Anti-Bacterial AgentsDisease OutbreaksElectrophoresis, Gel, Pulsed-FieldHospital UnitsHumansKidney TransplantationKlebsiella InfectionsKlebsiella oxytocaMicrobial Sensitivity TestsPoint MutationPromoter Regions, Geneticbeta-Lactam Resistancebeta-Lactamases

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18417660