The case of a 34 year-old woman with multiple lithiasis of Wirsung's duct who underwent a modified Puestow's operation is presented. Two (2) months after the surgery, the patient entered with a severe pain chart compatible with acute pancreatitis as a result of chronic pancreatitis. A very large lithiasis is observed in the head of the pancreas. Therapeutic procedure, pancreatic sphincterotomy and mechanical lithotripsy are performed. The procedure is described and the literature is reviewed.