Immune Responses to SARS-CoV, MERS-CoV and SARS-CoV-2.
Adv Exp Med Biol. 2020; 1288:5-12.AE

Abstract

The world has given an outbreak alarm in the last two decades, with different members of the coronavirus family infecting people at different times. The spread of the SARS-CoV-2 virus, which last appeared in December 2019 in China and spread rapidly to all over the world, has led the scientific world to studies on these viruses. While scientists are trying to develop vaccines or drugs against the virus, the body's immune response to the virus is emerged the biggest guide. In this review, we aimed to provide a good view on immune strategies by comparing immunological responses to SARS-CoV-2 disease among other members of the family, SARS-CoV and MERS-CoV. In the near future, it may contribute to vaccine or drug studies to be developed on immune intervention.

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Publisher Full Text (DOI)

Authors+Show Affiliations

İnandıklıoğlu N
Department of Medical Biology, Yozgat Bozok University Faculty of Medicine, Yozgat, Turkey.
Akkoc T
Department of Pediatric Allergy and Immunology, Marmara University Faculty of Medicine, İstanbul, Turkey. tuncakkoc@marmara.edu.tr.

MeSH

BetacoronavirusCOVID-19Coronavirus InfectionsHumansMiddle East Respiratory Syndrome CoronavirusPandemicsPneumonia, ViralSARS VirusSARS-CoV-2Severe Acute Respiratory Syndrome

Pub Type(s)

Comparative Study
Journal Article
Review

Language

eng

PubMed ID

32514817