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("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV)
336,581 results
  • Magnetic hydrogel particles improve nanopore sequencing of SARS-CoV-2 and other respiratory viruses. [Journal Article]
    Sci Rep. 2023 Feb 07; 13(1):2163.Andersen P, Barksdale S, … Lepene B
  • Presented here is a magnetic hydrogel particle enabled workflow for capturing and concentrating SARS-CoV-2 from diagnostic remnant swab samples that significantly improves sequencing results using the Oxford Nanopore Technologies MinION sequencing platform. Our approach utilizes a novel affinity-based magnetic hydrogel particle, circumventing low input sample volumes and allowing for both rapid m…
  • The role of digital technology in surgical home hospital programs. [Review]
    NPJ Digit Med. 2023 Feb 07; 6(1):22.Pathak K, Marwaha JS, Tsai TC
  • Home hospital (HH), a care delivery model of providing hospital-grade care to patients in their homes, has become increasingly common in medical settings, though surgical uptake has been limited. HH programs have been shown to be safe and effective in a variety of medical contexts, with increased usage of this care pathway during the COVID-19 pandemic. Though surgical patients have unique clinica…
  • Optimal spatial evaluation of a pro rata vaccine distribution rule for COVID-19. [Journal Article]
    Sci Rep. 2023 Feb 07; 13(1):2194.Castonguay FM, Blackwood JC, … Sanchirico JN
  • The COVID-19 Vaccines Global Access (COVAX) is a World Health Organization (WHO) initiative that aims for an equitable access of COVID-19 vaccines. Despite potential heterogeneous infection levels across a country, countries receiving allotments of vaccines may follow WHO's allocation guidelines and distribute vaccines based on a jurisdictions' relative population size. Utilizing economic-epidemi…
  • Prospective cohort study of Cryptosporidium infection and shedding in infants and their households. [Journal Article]
    Clin Infect Dis. 2023 Feb 08 [Online ahead of print]Korpe P, Ni Z, … Duggal P
  • CONCLUSIONS: In this intensive, longitudinal study of Cryptosporidium infection in families we found high rates of cryptosporidiosis in infants and children, and prolonged parasite shedding, especially among malnourished children. These data support that transmission within the household is an important route of exposure for young infants, and that treatment of non-diarrheal infection to interrupt person-to-person transmission within the home may be essential for preventing cryptosporidiosis in infants.
  • Telehealth's future in Australian Primary Health Care: Lessons from the COVID-19 Pandemic. [Journal Article]
    BJGP Open. 2023 Feb 07 [Online ahead of print]Ashley C, Williams A, … Halcomb E
  • CONCLUSIONS: Providers required resilience and flexibility to adapt to telehealth. Funding models mustreward providers from an outcome focus, rather than placing limits on telehealth's use.Hybrid approaches to service delivery will best meet the needs of the community but mustbe accompanied by support and education for PHC professionals.
  • T Cell Responses to SARS-CoV-2. [Review]
    Annu Rev Immunol. 2022 Feb 07 [Online ahead of print]Sette A, Sidney J, Crotty S
  • A large body of evidence generated in the last two and a half years addresses the roles of T cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces multi-epitope CD4 and CD8 T cell responses with polyfunctionality. Early T cell responses have been associated with mild COVID-19 outcomes. In concert with animal model data, these results suggest that while antibody…
  • Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS. [Journal Article]
    BMJ Case Rep. 2023 Feb 07; 16(2)Babu VK, Rojas P, … Garcia-Fernandez A
  • An elderly man presenting with shortness of breath and hypoxaemia was admitted with acute hypoxic respiratory failure secondary to COVID-19 pneumonia. Due to worsening hypoxaemia, he was transferred to the intensive care unit and required mechanical ventilation. Propofol was infused at 1.5-4 mg/kg/hour. Within 48 hours of initiation, we noticed worsening metabolic acidosis, acute kidney injury, h…
  • Canadians' opinions towards COVID-19 data-sharing: a national cross-sectional survey. [Journal Article]
    BMJ Open. 2023 Feb 07; 13(2):e066418.Savic Kallesoe SA, Rabbani T, … Hsiao WWL
  • CONCLUSIONS: These findings suggest that the Canadian public is generally favourable to deidentified data-sharing. Identifying factors that are likely to improve attitudes towards data-sharing are useful to stakeholders involved in data-sharing initiatives, such as public health agencies, in informing the development of public health communication and data-sharing policies. As Canada progresses through the COVID-19 pandemic, and with limited testing and reporting of COVID-19 data, it is essential to improve deidentified data-sharing given the public's general support for these efforts.
  • Hyaluronan in the Pathogenesis of Acute and Post-Acute COVID-19 Infection. [Review]
    Matrix Biol. 2023 Feb 05 [Online ahead of print]Barnes HW, Demirdjian S, … Bollyky PL
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently emerged as the cause of a global pandemic. Infection with SARS-CoV-2 can result in COVID-19 with both acute and chronic disease manifestations that continue to impact many patients long after the resolution of viral replication. There is therefore great interest in understanding the host factors that contribute to COVID-19 path…
  • Learning from community-based HIV prevention to inform control and mitigation of the COVID-19 pandemic. [Journal Article]
    Prev Med. 2023 Feb 05 [Online ahead of print]Abrams JA, Rutledge J, Opara I
  • The current COVID-19 pandemic and the likelihood of future viral pandemics demonstrate a need for strategic prevention campaigns that integrate biomedical, structural, and behavioral interventions within larger scale comprehensive public health initiatives. In Human Immunodeficiency Virus (HIV) prevention, community-based efforts have resulted in reductions in transmission rates, increases in tes…
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