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("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV) AND Journal Article[PT])
110,549 results
  • The Impact of COVID-19 on the Optimal Management of Osteoporosis. [Journal Article]
    J Bone Metab. 2021 May; 28(2):115-122.Kong SH, Hwang BK, Yoon BH
  • Osteoporosis does not take a break while Coronavirus disease 2019 (COVID-19) stunned and overtook everyone's lives. Medical resources were immediately shifted, self-isolation and telemedicine were expanded, ambulatory care services such as bone densitometry and osteoporosis-centered clinics came to a near halt. Progress with fracture prevention has been challenged because osteoporotic fracture wi…
  • Is Lupus Anticoagulant a Significant Feature of COVID-19? A Critical Appraisal of the Literature. [Journal Article]
    Semin Thromb Hemost. 2021 Jun 15 [Online ahead of print]Favaloro EJ, Henry BM, Lippi G
  • The term "lupus anticoagulant (LA)" identifies a form of antiphospholipid antibodies (aPLs) causing prolongation of clotting tests in a phospholipid concentration-dependent manner. LA is one of the laboratory criteria identified in patients with antiphospholipid (antibody) syndrome (APS). The presence of LA in patients with APS represents a significant risk factor for both thrombosis and pregnanc…
  • COVID-19 and Antiphospholipid Antibodies: Time for a Reality Check? [Journal Article]
    Semin Thromb Hemost. 2021 Jun 15 [Online ahead of print]Favaloro EJ, Henry BM, Lippi G
  • Antiphospholipid antibodies (aPL) comprise a panel of autoantibodies that reflect a potential prothrombotic risk in several autoimmune conditions, most notably antiphospholipid (antibody) syndrome (APS). aPL can be divided into those that form part of the laboratory criteria for APS, namely, lupus anticoagulant (LA), as well as anticardiolipin antibodies (aCL) and anti-β2-glycoprotein I antibodie…
  • COVID-19 versus SARS: A comparative review. [Review]
    J Infect Public Health. 2021 Apr 24; 14(7):967-977.Keshta AS, Mallah SI, … Tang P
  • The two genetically similar severe acute respiratory syndrome coronaviruses, SARS-CoV-1 and SARS-CoV-2, have each been responsible for global epidemics of vastly different scales. Although both viruses arose from similar origins, they quickly diverged due to differences in their transmission dynamics and spectrum of clinical presentations. The potential involvement of multiple organs systems, inc…
  • The immunological response among COVID-19 patients with acute respiratory distress syndrome. [Review]
    J Infect Public Health. 2021 May 26; 14(7):954-959.Almutairi AS, Abunurah H, … Alqahtani MM
  • Coronavirus disease 2019 (COVID-19) often results in pneumonia and can lead to acute respiratory distress syndrome (ARDS). ARDS is one of the most significant causes of death in patients with COVID-19. The development of a "cytokine storm" in patients with COVID-19 causes progression to ARDS. In this scoping review, we investigated the effect of pro-inflammatory cytokines in inducing moderate and…
  • The impact of high-resolution structural data on stemming the COVID-19 pandemic. [Review]
    Curr Opin Virol. 2021 Jun 03; 49:127-138.Cox RM, Plemper RK
  • The coronavirus disease 2019 (COVID-19) pandemic has had a catastrophic impact on human health and the world economy. The response of the scientific community was unparalleled, and a combined global effort has resulted in the creation of vaccines in a shorter time frame than previously unimaginable. Reflecting this concerted effort, the structural analysis of the etiological agent, severe acute r…
  • Technical framework for wastewater-based epidemiology of SARS-CoV-2. [Journal Article]
    Sci Total Environ. 2021 Jun 11; 791:148271.Wu J, Wang Z, … Yang K
  • Wastewater-based epidemiology (WBE) is expected to become a powerful tool to monitor the dissemination of SARS-CoV-2 at the community level, which has attracted the attention of scholars all over the world. However, there is not yet a standard protocol to guide its implementation. In this paper, we proposed a comprehensive technical and theoretical framework of relative quantification via qPCR fo…
  • Telehealth Sustainability in a Neurosurgery Department During the COVID-19 Pandemic. [Journal Article]
    World Neurosurg. 2021 Jun 12 [Online ahead of print]Chau MJ, Quintero JE, … van Horne C
  • CONCLUSIONS: TH visits were challenging due to the need for in-person physical exams in neurosurgery. TH temporarily accommodated patient needs during the pandemic but could not totally replace in-person visits, and was not sustained after 3.5 months of use. Video TH visits worked well for non-urgent issues and such as minor visual examinations. Our findings could help guide the implementation of TH should similar circumstances arise again.
  • Inhaled bronchodilators use and clinical course of adult inpatients with Covid-19 pneumonia in Spain: A retrospective cohort study. [Journal Article]
    Pulm Pharmacol Ther. 2021 Jun 12 [Online ahead of print]Villamañán E, Sobrino C, … Álvarez-Sala R
  • CONCLUSIONS: Off-label indication of inhaled-bronchodilators for Covid-19 patients are common in admitted patients. Taken on account our results, the use of IB for coronavirus pneumonia apparently is not associated with a significantly patient´s improvement. Our study confirms the hypothesis that inhaled bronchodilators do not improve clinical outcomes or reduce the risk of Covid-19 mortality. This could be due to the fact that the virus mainly affects the lung parenchyma and the pulmonary vasculature and probably not the airway. More researches are necessary in order to fill the gap in evidence for this new indication.
  • MHC Phosphopeptides: Promising targets for immunotherapy of cancer and other chronic diseases. [Review]
    Mol Cell Proteomics. 2021 Jun 12 [Online ahead of print]Mahoney KE, Shabanowitz J, Hunt DF
  • Major histocompatibility complex (MHC)-associated peptides have been considered as potential immunotherapeutic targets for many years. MHC class I phosphopeptides result from dysregulated cell signaling pathways that are common across cancers and both viral and bacterial infections. These antigens are recognized by central memory T-cells from healthy donors, indicating that they are considered an…
  • Antibody Responses After mRNA-Based COVID-19 Vaccination in Residential Older Adults: Implications for Reopening. [Journal Article]
    J Am Med Dir Assoc. 2021 Jun 12 [Online ahead of print]Nace DA, Kip KE, … Wells A
  • CONCLUSIONS: Higher functioning, healthier, residential older adults mounted detectable antibody responses when vaccinated with mRNA-based COVID-19 vaccines. Data suggests some degree of immunity is present during the immediate period following vaccination. However, protective effects remain to be determined in larger studies as clinical protection is afforded by ongoing adaptive immunity, which is known to be decreased in older adults. This study provides important preliminary results on level of population risk in older adult residents at assisted living, personal care, and independent living communities to inform reopening strategies, but are not likely to be translatable for residents in nursing homes.
  • Localized Cutaneous Reaction to a mRNA COVID-19 Vaccine. [Journal Article]
    J Cosmet Dermatol. 2021 Jun 15 [Online ahead of print]Edriss M, Farshchian M, Daveluy S
  • The corona virus disease (COVID-19) is a novel disease that can lead to fatal outcomes in infected individuals. Messenger RNA (mRNA) vaccines are two of the three Food and Drug Administration (FDA) approved vaccines in the United States (US) to date. Disclosed side effects by the Centers for Disease Control and Prevention (CDC) included tiredness, headache, muscle pain, chills, fever, and nausea.…
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