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("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV) AND Journal Article[PT])
12,809 results
  • Stroke care during the Covid-19 pandemic: Experience from three large European countries. [Review]
    Eur J Neurol. 2020 Jun 03 [Online ahead of print]Bersano A, Kraemer M, … Pantoni L
  • To cope with the exponentially increasing number of patients infected by SARS-Cov-2, European countries carried out enormous efforts to reorganize medical assistance, and several diseases, including stroke, were particularly impacted. Herein, we report the experience of stroke neurologists from three European countries, Italy, France and Germany, that faced the pandemic at diverse time points and…
  • Ethical Framework for Nutrition Support Resource Allocation During Shortages: Lessons From COVID-19. [Journal Article]
    Nutr Clin Pract. 2020 Jun 03 [Online ahead of print]Barrocas A, Schwartz DB, … Mueller CM
  • The coronavirus disease (COVID-19) pandemic has impacted all aspects of our population. The "Troubling Trichotomy" of what can be done technologically, what should be done ethically, and what must be done legally is a reality during these unusual circumstances. Recent ethical considerations regarding allocation of scarce resources, such as mechanical ventilators, have been proposed. These can app…
  • [Cardiac biomarkers and COVID-19 - Phenotypes and Interpretation]. [Journal Article]
    Dtsch Med Wochenschr. 2020 Jun; 145(11):755-760.Salbach C, Giannitsis E
  • Current pandemic caused by SARS-CoV-2 inducing viral COVID-19 pneumonia, is categorized in 3 stages. Some biomarkers could be assigned to one of these stages, showing a correlation to mortality in COVID-19 patients. Laboratory findings in COVID-19, especially when serially evaluated, may represent individual disease severity and prognosis. These may help planning and controlling therapeutic inter…
  • [SARS-CoV-2 infection (COVID-19): what can we expect?] [Journal Article]
    Dtsch Med Wochenschr. 2020 Jun; 145(11):740-746.Kern WV, Biever PM, … Panning M
  • - Case numbers in China are clearly declining, case numbers in many European regions are no longer increasing exponentially.- Data on mortality from SARS-CoV-2 infection are contradictory; mortality is certainly lower than for SARS and MERS, but probably higher than for most seasonal flu outbreaks in recent years- The main complication of SARS-CoV-2 infection is pneumonia with development of acut…
  • COVID-19 Pandemic and Role of Human Saliva as a Testing Biofluid in Point-of-Care Technology. [Journal Article]
    Eur J Dent. 2020 Jun 03 [Online ahead of print]Hamid H, Khurshid Z, … Zohaib S
  • Novel coronavirus disease 2019 (COVID-19) outbreak has termed as a controllable pandemic, and the entire world has come to a standstill trying to mitigate the disease with health systems. Health care providers, around the globe, are fighting day and night. Currently, rapid testing is taking place with the help of nasopharyngeal, oropharyngeal swab, bronchoalveolar lavage, sputum, urine, and blood…
  • COVID and Coagulation: Bleeding and Thrombotic Manifestations of SARS-CoV2 Infection. [Journal Article]
    Blood. 2020 Jun 03 [Online ahead of print]Al-Samkari H, Karp Leaf RS, … Rosovsky RP
  • Patients with coronavirus disease 2019 (COVID-19) have elevated D-dimer levels. Early reports describe high venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC) rates, but data are limited. This multicenter, retrospective study described the rate and severity of hemostatic and thrombotic complications of 400 hospital-admitted COVID-19 patients (144 critically ill) primari…
  • COVID-19's impact on the atmospheric environment in the Southeast Asia region. [Journal Article]
    Sci Total Environ. 2020 May 25; 736:139658.Kanniah KD, Kamarul Zaman NAF, … Latif MT
  • Since its first appearance in Wuhan, China at the end of 2019, the new coronavirus (COVID-19) has evolved a global pandemic within three months, with more than 4.3 million confirmed cases worldwide until mid-May 2020. As many countries around the world, Malaysia and other southeast Asian (SEA) countries have also enforced lockdown at different degrees to contain the spread of the disease, which h…
  • Role of a habitat's air humidity in Covid-19 mortality. [Journal Article]
    Sci Total Environ. 2020 May 22; 736:138763.Biktasheva IV
  • Transient local over-dry environment might be a contributor and an explanation for the observed asynchronous local rises in Covid-19 mortality. We propose that a habitat's air humidity negatively correlate with Covid-19 morbidity and mortality, and support this hypothesis on the example of publicly available data from German federal states.
  • Impact of COVID-19 outbreak measures of lockdown on the Italian Carbon Footprint. [Journal Article]
    Sci Total Environ. 2020 May 29; 737:139806.Rugani B, Caro D
  • Stringent lockdown measures implemented in Italy to mitigate the spread of COVID-19 are generating unprecedented economic impacts. However, the environmental consequences associated with the temporary shutdown and recovery of industrial and commercial activities are still not fully understood. Using the well-known carbon footprint (CF) indicator, this paper provides a comprehensive estimation of …
  • Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19? [Journal Article]
    Med Hypotheses. 2020 May 18; 143:109843.Abeygunasekera A, Jayasinghe S
  • SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19. Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority. The paper proposes evidence for the potential use of diethylcarbamazine (DEC) in the treatment of COVID-19. DEC has inhibitory effects on arachidonic acid metabolism to pr…
  • Pandemic Preparedness: Developing Vaccines and Therapeutic Antibodies For COVID-19. [Review]
    Cell. 2020 May 27 [Online ahead of print]Sempowski GD, Saunders KO, … Haynes BF
  • The SARS-CoV-2 pandemic that causes COVID-19 respiratory syndrome has caused global public health and economic crises, necessitating rapid development of vaccines and therapeutic countermeasures. The world-wide response to the COVID-19 pandemic has been unprecedented with government, academic, and private partnerships working together to rapidly develop vaccine and antibody countermeasures. Many …
  • Proteomic and Metabolomic Characterization of COVID-19 Patient Sera. [Journal Article]
    Cell. 2020 May 28 [Online ahead of print]Shen B, Yi X, … Guo T
  • Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a training cohort of 18 non-severe and 13 severe patients. The model was validated using 10 independent pat…
  • Rationale and Design of ORCHID: A Randomized Placebo-Controlled Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19. [Journal Article]
    Ann Am Thorac Soc. 2020 Jun 03 [Online ahead of print]Casey JD, Johnson NJ, … ORCHID Protocol Committee and the National Heart, Lung and Blood Institute Prevention and Early Treatment of Acute Lung Injury (PETAL) Network Investigators
  • The Outcomes Related to COVID-19 treated with Hydroxychloroquine among In-patients with symptomatic Disease (ORCHID) trial is a multicenter, blinded, randomized trial of hydroxychloroquine versus placebo for the treatment of adults hospitalized with COVID-19. This document provides the rationale and background for the trial and highlights key design features. We discuss five novel challenges to t…
  • A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19. [Journal Article]
    N Engl J Med. 2020 Jun 03 [Online ahead of print]Boulware DR, Pullen MF, … Hullsiek KH
  • CONCLUSIONS: After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid-19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure. (Funded by David Baszucki and Jan Ellison Baszucki and others; ClinicalTrials.gov number, NCT04308668.).
  • Two hits to the renin-angiotensin system may play a key role in severe COVID-19. [Review]
    Kaohsiung J Med Sci. 2020 Jun 03 [Online ahead of print]Tseng YH, Yang RC, Lu TS
  • The spike glycoprotein on the virion surface docking onto the angiotensin-converting enzyme (ACE) 2 dimer is an essential step in the process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in human cells-involves downregulation of ACE2 expression with systemic renin-angiotensin system (RAS) imbalance and promotion of multi-organ damage. In general, the RAS induces vasoc…
  • Review of the present features and the infection control challenges of COVID-19 pandemic in dialysis facilities. [Review]
    Kaohsiung J Med Sci. 2020 Jun 03 [Online ahead of print]Lee JJ, Hwang SJ, Huang JF
  • The COVID-19 has swept the world causing suffering, death, loss, and massive economy damage. The dialysis population is vulnerable and the dialysis facility is critical in maintaining operations and avoiding disease transmission. The present information regarding the clinical features of COVID-19 infection in the dialysis population was collected, and the useful measures of COVID-19 infection pre…
  • Clinical Manifestations of Children with COVID-19: a Systematic Review. [Review]
    Pediatr Pulmonol. 2020 Jun 03 [Online ahead of print]de Souza TH, Nadal JA, … Brandão MB
  • CONCLUSIONS: Clinical manifestations of children with COVID-19 differ widely from adults cases. Fever and respiratory symptoms should not be considered a hallmark of COVID-19 in children. This article is protected by copyright. All rights reserved.
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