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((Adult Respiratory Distress Syndrome OR ARDS) AND ("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV))
4,037 results
  • [Deafness after COVID-19? German version]. [Journal Article]
    HNO. 2021 Apr 09 [Online ahead of print]Gerstacker K, Speck I, … Arndt S
  • This article presents a case of sudden bilateral deafness in the context of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and resultant coronavirus disease 2019 (COVID-19). After treatment in the intensive care unit for acute respiratory distress syndrome and acute kidney failure, hearing ability had drastically changed. While hearing had been subjectively normal before …
  • IL-6 modulation for COVID-19: the right patients at the right time? [Review]
    J Immunother Cancer. 2021 Apr; 9(4)Ascierto PA, Fu B, Wei H
  • The ongoing pandemic caused by the novel coronavirus SARS-CoV-2 has disrupted the global economy and strained healthcare systems to their limits. After the virus first emerged in late 2019, the first intervention that demonstrated significant reductions in mortality for severe COVID-19 in large-scale trials was corticosteroids. Additional options that may reduce the burden on the healthcare syste…
  • SARS-CoV 2 Infection (Covid-19) and Cardiovascular Disease in Africa: Health Care and Socio-Economic Implications. [Review]
    Glob Heart. 2021 Mar 15; 16(1):18.Ogah OS, Umuerri EM, … Sliwa K
  • The current pandemic of SARS-COV 2 infection (Covid-19) is challenging health systems and communities worldwide. At the individual level, the main biological system involved in Covid-19 is the respiratory system. Respiratory complications range from mild flu-like illness symptoms to a fatal respiratory distress syndrome or a severe and fulminant pneumonia. Critically, the presence of a pre-existi…
  • The role of extracorporeal membrane oxygenation in critically ill patients with COVID-19: a narrative review. [Review]
    BMC Pulm Med. 2021 Apr 08; 21(1):116.Huang S, Zhao S, … Chen X
  • Extracorporeal life support treatments such as extracorporeal membrane oxygenation (ECMO) have been recommended for the treatment of severe acute respiratory distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). To date, many countries, including China, have adopted ECMO as a treatment for severe COVID-19. However, marked differences in patient survival rates have been repor…
  • Pediatric radiologic manifestations of COVID-19. [Journal Article]
    Clin Imaging. 2021 Mar 30; 75:165-170.Romberg EK, Menashe SJ, … Otjen JP
  • CONCLUSIONS: Radiologic findings of COVID-19 in pediatric patients range from normal to severe ARDS type appearance. During this ongoing pandemic, these radiographic signs can be useful for the evaluation of disease status and guiding care, particularly in those with comorbidities.Radiologic findings of COVID-19 in pediatric patients are similar to those seen in adults, and may range from normal to severe ARDS type appearance.
  • Implications of SARS-Cov-2 infection on eNOS and iNOS activity: consequences for the respiratory and vascular systems. [Review]
    Nitric Oxide. 2021 Apr 05 [Online ahead of print]Guimarães L, Rossini CVT, Lameu C
  • Symptoms of COVID-19 range from asymptomatic/mild symptoms to severe illness and death, consequence of an excessive inflammatory process triggered by SARS-CoV-2 infection. The diffuse inflammation leads to endothelium dysfunction in pulmonary blood vessels, uncoupling eNOS activity, lowering NO production, causing pulmonary physiological alterations and coagulopathy. On the other hand, iNOS activ…
  • COVID-19 severe pneumonia: Prospective multicentre study on demands on intensive care capacities. [Journal Article]
    Cent Eur J Public Health. 2021 Mar; 29(1):3-8.Džupová O, Moravec M, … Beneš J
  • CONCLUSIONS: Sufficient number of intensive care beds, organ support equipment and well-trained staff is a decisive factor in managing the COVID-19 epidemic. The study focused on the needs of intensive care in the COVID-19 patients. Advanced age and acute kidney injury were identified as independent predictors for in-hospital mortality. When compared to clinical course and ICU management of patients with severe community-acquired pneumonia caused by other pathogens, we observed prolonged need for ventilatory support, high rate of progression to acute respiratory distress syndrome and significant mortality in studied population.
  • COVID-19 and ARDS: Update On Preventive And Therapeutic Venues. [Journal Article]
    Curr Mol Med. 2021 Apr 07 [Online ahead of print]Narota A, Puri G, … Naura AS
  • A novel coronavirus SARS-CoV-2 which initially originated in China has outstretched to all nations and turned out to be an intense global concern for both the governments and the public. In addition to the health concerns, COVID-19 pandemic has caused tremendous impact on economic and political conditions of every nation. Ever since the start of pandemic the physicians were constrained to rely on…
  • Post-COVID pulmonary fibrosis: therapeutic efficacy using with mesenchymal stem cells - How the lung heals. [Journal Article]
    Eur Rev Med Pharmacol Sci. 2021 Mar; 25(6):2748-2751.Vishnupriya M, Naveenkumar M, … Arul N
  • COVID-19 is an acute respiratory infectious disease caused by SARS-COV 2 (Severe Acute Respiratory Syndrome Coronavirus) that has become a global pandemic. COVID-19 mainly causes the respiratory complications of Acute Respiratory Distress Syndrome (ARDS), cytokine storm, and severe immune disruptions. The assays depict that though people recuperate from COVID-19, there are still symptoms that per…
  • Carbon-Based Nanomaterials: Promising Antiviral Agents to Combat COVID-19 in the Microbial-Resistant Era. [Journal Article]
    ACS Nano. 2021 Apr 07 [Online ahead of print]Serrano-Aroca Á, Takayama K, … Brufsky A
  • Therapeutic options for the highly pathogenic human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing the current pandemic coronavirus disease (COVID-19) are urgently needed. COVID-19 is associated with viral pneumonia and acute respiratory distress syndrome causing significant morbidity and mortality. The proposed treatments for COVID-19 have shown little or no effect in the c…
  • Variation in Initial U.S. Hospital Responses to the Coronavirus Disease 2019 Pandemic. [Journal Article]
    Crit Care Med. 2021 Apr 08 [Online ahead of print]Mathews KS, Seitz KP, … National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury (PETAL) Clinical Trials Network
  • CONCLUSIONS: The coronavirus disease 2019 pandemic prompted widespread system-level changes, but front-line clinical care varied widely according to specific hospital needs and infrastructure. Linking operational changes to care delivery processes is a necessary step to understand the impact of the coronavirus disease 2019 pandemic on patient outcomes.
  • Pharmacokinetic and Pharmacodynamic Evaluation of Ravulizumab in Adults with Severe Coronavirus Disease 2019. [Journal Article]
    Infect Dis Ther. 2021 Apr 07 [Online ahead of print]McEneny-King AC, Monteleone JPR, … Ortiz SR
  • CONCLUSIONS: High levels of baseline C5 observed in patients with severe COVID-19 contribute to the growing body of evidence that suggests this disease is marked by amplification of terminal complement activation. Data from this preliminary pharmacokinetic/pharmacodynamic evaluation of 22 patients with severe COVID-19 show that the modified ravulizumab dosing regimen achieved immediate and complete terminal complement inhibition, which can be sustained for up to 22 days. These data support the continued use of this dosage regimen in the ongoing phase 3 study.
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