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((Pneumonia OR Pulmonary OR ARDS) AND ("Novel Coronavirus" OR COVID-19 OR SARS-CoV-2 OR 2019-nCoV))
77,384 results
  • E-cigarette Vape and Lung ACE2 Expression: Implications for coronavirus vulnerability. [Journal Article]
    Environ Toxicol Pharmacol. 2021 Apr 07 [Online ahead of print]Lallai V, Manca L, Fowler CD
  • Evidence in humans suggests a correlation between nicotine smoking and severe respiratory symptoms with COVID-19 infection. In lung tissue, angiotensin-converting enzyme 2 (ACE2) appears to mechanistically underlie viral entry. Here, we investigated whether e-cigarette vapor inhalation alters ACE2 and nicotinic acetylcholine receptor (nAChR) expression in male and female mice. In male lung, nicot…
  • Pathobiology questions raised by telogen effluvium and trichodynia in COVID-19 patients. [Letter]
    Exp Dermatol. 2021 Apr 10 [Online ahead of print]Di Landro A, Naldi L, … Tosti A
  • We recently observed 39 patients in Italy presenting with telogen effluvium, including 7 patients with severe trichodynia. These include 9 men and 30 women ageing 48 to 73 years (mean age 64.6). In 16 patients, COVID-19 presented with severe interstitial pneumonia, requiring hospitalization and Continuous Positive Airway Pressure (CPAP) therapy. Medications included paracetamol (39) systemic ster…
  • Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm. [Journal Article]
    Adv Mater. 2021 Apr 10 [Online ahead of print]Meng QF, Tian R, … Rao L
  • The COVID-19 pandemic, induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused great impact on the global economy and people's daily life. In the clinic, most patients with COVID-19 show none or mild symptoms, while approximately 20% of them develop severe pneumonia, multiple organ failure, or septic shock due to infection-induced cytokine release syndrome (the so-call…
  • Lobectomy with pathological examination in lung cancer patients who recovered from COVID-19. [Journal Article]
    Gen Thorac Cardiovasc Surg. 2021 Apr 09 [Online ahead of print]Nefedov A, Mortada M, … Yablonskii P
  • We present two cases of lobectomy in lung cancer patients who recovered from COVID-19 before surgical treatment. In both cases, video-assisted thoracoscopic surgery was initiated and hilar fibrosis was detected; as a result, conversion was performed in one case. There were no postoperative complications and mortality. Also, we demonstrate the results of pathological examination in patients who ha…
  • [Deafness after COVID-19? German version]. [Journal Article]
    HNO. 2021 Apr 09 [Online ahead of print]Gerstacker K, Speck I, … Arndt S
  • This article presents a case of sudden bilateral deafness in the context of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection and resultant coronavirus disease 2019 (COVID-19). After treatment in the intensive care unit for acute respiratory distress syndrome and acute kidney failure, hearing ability had drastically changed. While hearing had been subjectively normal before …
  • IL-6 modulation for COVID-19: the right patients at the right time? [Review]
    J Immunother Cancer. 2021 Apr; 9(4)Ascierto PA, Fu B, Wei H
  • The ongoing pandemic caused by the novel coronavirus SARS-CoV-2 has disrupted the global economy and strained healthcare systems to their limits. After the virus first emerged in late 2019, the first intervention that demonstrated significant reductions in mortality for severe COVID-19 in large-scale trials was corticosteroids. Additional options that may reduce the burden on the healthcare syste…
  • Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis. [Journal Article]
    ILAR J. 2021 Apr 09 [Online ahead of print]Zeiss CJ, Compton S, Veenhuis RT
  • The Coronavirus Disease 2019 (COVID-19) pandemic has fueled unprecedented development of animal models to understand disease pathogenesis, test therapeutics, and support vaccine development. Models previously developed to study severe acute respiratory syndrome coronavirus (SARS-CoV) have been rapidly deployed to study SARS-CoV-2. However, it has become clear that despite the common use of ACE2 a…
  • Focused Role of Nanoparticles Against COVID-19: Diagnosis and Treatment. [Review]
    Photodiagnosis Photodyn Ther. 2021 Apr 06 [Online ahead of print]Dheyab MA, Khaniabadi PM, … Khaleel HA
  • The 2019 novel coronavirus (2019-nCoV; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)) has witnessed a rapid and global proliferation since its early identification in patients with severe pneumonia in Wuhan, China. As of 27th May 2020, 2019-nCoV cases have risen to >5 million, with confirmed deaths of 350,000. However, Coronavirus disease (COVID-19) diagnostic and treatment measure…
  • TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation. [Journal Article]
    Cell. 2021 Mar 30 [Online ahead of print]Ho JSY, Mok BW, … Marazzi I
  • The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently affecting millions of lives worldwide. Large retrospective studies indicate that an elevated level of inflammatory cytokines and pro-inflammatory factors are associated with both increased disease severity and mortality. Here, using multidimensional epigenetic, transcriptional, in vitro, and i…
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