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(1 25 dihydroxycholecalciferol)
23,819 results
  • Hungry bone syndrome after parathyroid surgery. [Journal Article]
    Hemodial Int. 2023 Jan 31 [Online ahead of print]Tai YL, Shen HY, … Yen TH
  • CONCLUSIONS: Hungry bone syndrome is common (83.3%) after parathyroidectomy for secondary hyperparathyroidism in patients undergoing hemodialysis, and this complication should be monitored and managed appropriately.
  • Systematic Review of the Treatment of Persistent Hyperparathyroidism Following Kidney Transplantation. [Review]
    Biomedicines. 2022 Dec 22; 11(1)Miedziaszczyk M, Lacka K, … Idasiak-Piechocka I
  • Chronic kidney disease-mineral and bone disorder is one of the complications associated with chronic kidney disease. About 10-50% of patients following kidney transplantation have persistent hyperparathyroidism. Hypercalcaemic hyperparathyroidism has a negative impact on the kidney transplant outcome; therefore, it requires treatment. The data regarding the treatment of persistent hyperparathyroi…
  • Pembrolizumab Induced Calcitriol-Mediated Hypercalcemia. [Case Reports]
    Case Rep Nephrol. 2023; 2023:9160326.Oommen TT, Sun K, … Kim M
  • PD-1/PD-L1 inhibitors such as pembrolizumab have radically improved the prognosis for many patients with advanced malignancies. Although revolutionary, its use can be complicated and limited by various immune-related adverse effects. Effective management depends on early recognition and prompt intervention. Herein, we describe a unique syndrome of hypercalcemia, with associated acute renal injury…
  • [The 499th case: Roux-en-Y gastric bypass, limb weakness, and ostealgia]. [Case Reports]
    Zhonghua Nei Ke Za Zhi. 2023 Jan 01; 62(1):117-121.Song A, Yang Y, … Wang O
  • A 36-year-old woman was admitted to the Peking Union Medical College Hospital with a history of fractures for 2 years, limb weakness for 1 year, and ostealgia for 2 months. The patient's examination identified iron deficiency anemia, significantly decreased serum calcium and 25-hydroxyvitamin D3 levels, and increased alkaline phosphatase and parathyroid hormone levels. Imaging showed several typi…
  • Subtotal parathyroidectomy successfully controls calcium levels of patients with neonatal severe hyperparathyroidism carrying a novel CASR mutation. [Case Reports]
    Horm Res Paediatr. 2023 Jan 10 [Online ahead of print]Wejaphikul K, Dejkhamron P, … Kantaputra P
  • CONCLUSIONS: We report a novel heterozygous and homozygous missense variant (c.1817T>C; p.Leu606Pro) in CASR in two NSHPT patients. The mutation likely disrupts conformational changes of CASR and results in cinacalcet unresponsiveness. Intronic variants in CASR identified in the patient with heterozygous variant might have contributed to the clinical manifestations of the patient. Although total parathyroidectomy is wildly accepted as a standard treatment for NSHPT, we demonstrate that subtotal parathyroidectomy is also an effective procedure to normalize Ca levels and allow these patients to be in normocalcemia or mild hypoparathyroidism, which is simply controlled by low-dose calcitriol treatment. Subtotal parathyroidectomy appeared to be an effective treatment for NSHPT regardless of the molecular etiologies.
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