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(1 25 dihydroxycholecalciferol)
10,808 results
  • Mechanisms of Hypercalcemia in Non-Hodgkin Lymphoma and Associated Outcomes: A Retrospective Review. [Journal Article]
  • CLClin Lymphoma Myeloma Leuk 2018; 18(2):e123-e129
  • Shallis RM, Rome RS, Reagan JL
  • CONCLUSIONS: The major mechanism by which NHL patients develop hypercalcemia is not mediated by calcitriol or PTHrP. Hypercalcemia is most prevalent in patients with diffuse large B-cell lymphoma of the nongerminal cell subtype. Patients with calcitriol-mediated hypercalcemia showed a trend toward worse outcomes, suggesting that calcitriol might be a marker of high-grade lymphoma, transformation to such, or a surrogate for more advanced disease.
  • Placental vitamin D metabolism and its associations with circulating vitamin D metabolites in pregnant women. [Randomized Controlled Trial]
  • AJAm J Clin Nutr 2017; 106(6):1439-1448
  • Park H, Wood MR, … Caudill MA
  • CONCLUSIONS: The numerous associations of many of the placental biomarkers of vitamin D metabolism with circulating vitamin D metabolites among pregnant women [including a CYP27B1-associated increase in 1,25(OH)2D3] and the evidence of trophoblast production and secretion of vitamin D metabolites, especially 25(OH)D3, suggest that the placenta may play an active role in modulating the vitamin D metabolite profile in maternal circulation in human pregnancy. This trial was registered at clinicaltrials.gov as NCT03051867.
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