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143 results
  • Addressing tuberculosis among Inuit in Canada. [Journal Article]
    Can Commun Dis Rep 2018; 44(3-4):82-85Patterson M, Flinn S, Barker K
  • The average annual rate of tuberculosis (TB) among Inuit in Canada is now more than 290 times higher than Canadian born non-Indigenous people. How did this happen? Using the Territory of Nunavut as a case example, the roots of this situation can largely be traced back to social determinants of health and challenges in access to health care. Half (52%) of all Nunavut residents live in social housi…
  • Identification of a novel advanced glycation end product derived from lactaldehyde. [Journal Article]
    Biosci Biotechnol Biochem 2019; 83(6):1136-1145Fujimoto S, Murakami Y, … Watanabe H
  • Advanced glycation end products (AGEs) are implicated in the development of diabetic complications via the receptor for AGEs (RAGE). We have reported that the 3-hydroxypyridinium (3HP)-containing AGEs derived from α-hydroxyaldehydes physically interact with RAGE and show cytotoxicity. Lactaldehyde (LA) is formed from a reaction between threonine and myeloperoxidase, but no LA-derived AGEs have be…
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