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(5′ Ntase)
9 results
  • Structure-function analysis of the OB and latch domains of chlorella virus DNA ligase. [Journal Article]
    J Biol Chem 2011; 286(25):22642-52Samai P, Shuman S
  • Chlorella virus DNA ligase (ChVLig) is a minimized eukaryal ATP-dependent DNA sealing enzyme with an intrinsic nick-sensing function. ChVLig consists of three structural domains, nucleotidyltransferase (NTase), OB-fold, and latch, that envelop the nicked DNA as a C-shaped protein clamp. The OB domain engages the DNA minor groove on the face of the duplex behind the nick, and it makes contacts to …
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