- Influenza Vaccination and Incident Tuberculosis among Elderly Persons, Taiwan1. [Journal Article]
- EIEmerg Infect Dis 2018; 24(3):498-505
- Experimental studies have demonstrated that influenza vaccination may protect against tuberculosis (TB) through a Th17 response. This nationwide cohort study aimed to evaluate the association of infl...
Experimental studies have demonstrated that influenza vaccination may protect against tuberculosis (TB) through a Th17 response. This nationwide cohort study aimed to evaluate the association of influenza vaccination with incident TB among elderly persons in Taiwan. This 2005-2012 study included 99,982 elderly persons (64,290 vaccinated and 35,692 unvaccinated) from the Taiwan National Health Insurance Research Database. During the 738,367 person-years of follow-up, 1,141 (1.14%) persons had incident TB. The cumulative incidences of TB were 145.2 cases/100,000 person-years among vaccinated elderly persons and 175.5 cases/100,000 person-years among unvaccinated elderly persons (p = 0.002). The time-dependent Cox proportional hazards model revealed that influenza vaccination was an independent protective factor for incident TB. Our results suggest that influenza vaccination is associated with a lower risk of incident TB among elderly persons in Taiwan. Further investigation of biologic mechanisms is warranted.
- Physical activities (exercises or choreses) during pregnancy and mode of delivery in nulliparous women: A prospective cohort study. [Journal Article]
- TJTaiwan J Obstet Gynecol 2018; 57(1):18-22
- CONCLUSIONS: The results of this study showed that regular and standard physical activities during pregnancy can reduce the risk of caesarean section in pregnant women. These findings can be important in convincing health care providers to prescribe regular and standard physical activities for pregnant women during pregnancy.
- Validation of the French-Canadian Pelvic Girdle Questionnaire. [Journal Article]
- JMJ Manipulative Physiol Ther 2018 Feb 15
- CONCLUSIONS: Overall, the French-Canadian version of the PGQ is reliable, valid, and responsive, suggesting that it can be implemented in both research and clinical settings to assess functional limitations in pregnant and postpartum women.
- Milk losses associated with somatic cell counts by parity and stage of lactation. [Journal Article]
- JDJ Dairy Sci 2018 Feb 14
- The reduction of milk production caused by subclinical mastitis in dairy cows was evaluated through the regression of test-day milk yield on log-transformed somatic cell counts (LnSCC). Official test...
The reduction of milk production caused by subclinical mastitis in dairy cows was evaluated through the regression of test-day milk yield on log-transformed somatic cell counts (LnSCC). Official test-day records (n = 1,688,054) of Holstein cows (n = 87,695) were obtained from 719 herds from January 2010 to December 2015. Editing was performed to ensure both reliability and consistency for the statistical analysis, and the final data set comprised 232,937 test-day records from 31,692 Holstein cows in 243 herds. A segmented regression was fitted to estimate the cutoff point in the LnSCC scale where milk yield started to be affected by mastitis. The statistical model used to explain daily milk yield included the effect of herd as a random effect and days in milk and LnSCC as fixed effects regressions, and analyses were performed by parity and stage of lactation. The cutoff point where milk yield starts to be affected by changes in LnSCC was estimated to be around 2.52 (the average of all estimates of approximately 12,400 cells/mL) for Holsteins cows from Brazilian herds. For first-lactation cows, milk losses per unit increase of LnSCC had estimates around 0.68 kg/d in the beginning of the lactation [5 to 19 d in milk (DIM)], 0.55 kg/d in mid-lactation (110 to 124 DIM), and 0.97 kg/d at the end of the lactation (289 to 304 DIM). For second-lactation cows, milk losses per unit increase of LnSCC had estimates around 1.47 kg/d in the beginning of the lactation (5 to 19 DIM), 1.09 kg/d in mid-lactation (110 to 124 DIM), and 2.45 kg/d at the end of the lactation (289 to 304 DIM). For third-lactation cows, milk losses per unit increase of LnSCC had estimates around 2.22 kg/d in the beginning of the lactation (5 to 19 DIM), 1.13 kg/d in mid-lactation (140 to 154 DIM), and 2.65 kg/d at the end of the lactation (289 to 304 DIM). Daily milk losses caused by increased LnSCC were dependent on parity and stage of lactation, and these factors should be considered when estimating losses associated with subclinical mastitis.
- Relationship between vectorcardiographic QRSarea, myocardial scar quantification, and response to cardiac resynchronization therapy. [Journal Article]
- JEJ Electrocardiol 2018 Feb 08
- CONCLUSIONS: QRSareais inversely associated with focal scar on CMR. Incremental predictive value for CRT response is achieved by a combined CMR-QRSareaanalysis.
- Correlates of Postpartum Visits Among Medicaid Recipients: An Analysis Using Claims Data from a Managed Care Organization. [Journal Article]
- JWJ Womens Health (Larchmt) 2018 Feb 16
- CONCLUSIONS: Our results highlight factors associated with attendance of PPCVs in low income populations. The continued disparity in postpartum care utilization compels additional efforts to improve access to health services across socioeconomic and demographic boundaries.
- Antepartum risk factors for moderate to severe neonatal hypoxic ischemic encephalopathy: a Swedish national cohort study. [Journal Article]
- AOActa Obstet Gynecol Scand 2018 Feb 16
- CONCLUSIONS: Antepartum risk factors for moderate to severe HIE included nulliparity, previous cesarean delivery, short stature, overweight, gestational age, occiput posterior presentation, and birthweight. The combination of maternal short stature and overweight was associated with a more than threefold risk of subsequent HIE. This article is protected by copyright. All rights reserved.
- Observationally quantified reconnection providing a viable mechanism for active region coronal heating. [Journal Article]
- NCNat Commun 2018 Feb 15; 9(1):692
- The heating of the Sun's corona has been explained by several different mechanisms including wave dissipation and magnetic reconnection. While both have been shown capable of supplying the requisite ...
The heating of the Sun's corona has been explained by several different mechanisms including wave dissipation and magnetic reconnection. While both have been shown capable of supplying the requisite power, neither has been used in a quantitative model of observations fed by measured inputs. Here we show that impulsive reconnection is capable of producing an active region corona agreeing both qualitatively and quantitatively with extreme-ultraviolet observations. We calculate the heating power proportional to the velocity difference between magnetic footpoints and the photospheric plasma, called the non-ideal velocity. The length scale of flux elements reconnected in the corona is found to be around 160 km. The differential emission measure of the model corona agrees with that derived using multi-wavelength images. Synthesized extreme-ultraviolet images resemble observations both in their loop-dominated appearance and their intensity histograms. This work provides compelling evidence that impulsive reconnection events are a viable mechanism for heating the corona.
- CASQ1 Gene Is an Unlikely Candidate for Malignant Hyperthermia Susceptibility in the North American Population: Erratum. [Journal Article]
- AAnesthesiology 2018; 128(3):692
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- Bobbing of Oxysterols: Molecular Mechanism for Translocation of Tail-Oxidized Sterols through Biological Membranes. [Journal Article]
- JPJ Phys Chem Lett 2018 Feb 19; :1118-1123
- Translocation of sterols between cellular membrane leaflets is of key importance in membrane organization, dynamics, and signaling. We present a novel translocation mechanism that differs in a unique...
Translocation of sterols between cellular membrane leaflets is of key importance in membrane organization, dynamics, and signaling. We present a novel translocation mechanism that differs in a unique manner from the established ones. The bobbing mechanism identified here is demonstrated for tail-oxidized sterols, but is expected to be viable for any molecule containing two polar centers at the opposite sides of the molecule. The mechanism renders translocation across a lipid membrane possible without a change in molecular orientation. For tail-oxidized sterols, the bobbing mechanism provides an exceptionally facile means to translocate these signaling molecules across membrane structures and may thus represent an important pathway in the course of their biological action.