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8,705 results
  • Development of Drug Discovery Screening System by Molecular Interaction Kinetics Mass Spectrometry. [Journal Article]
  • RCRapid Commun Mass Spectrom 2018 Feb 14
  • Obi N, Fukuda T, … Kawamura T
  • CONCLUSIONS: Six small molecule binders of CAII were analyzed quantitatively using nPOI and MIK-MS, and the results were compared to published SPR results. The nPOI and SPR results show good agreement, confirming the reliability of the analysis. Time-dependent binding results may be obtained by our MS-sensorgram approach. Drugs that meet medical needs in a short period are required; this nPOI-LC-MS system is considered an important tool for rapid drug discovery.
  • GeneReviews® [BOOK]
  • BOOKUniversity of Washington, Seattle: Seattle (WA)
  • Adam MP, Ardinger HH, … Amemiya ARamnitz MS, Gafni RI, … Collins MT
  • Hyperphosphatemic familial tumoral calcinosis (HFTC) is characterized by: Ectopic calcifications (tumoral calcinosis) typically found in periarticular soft tissues exposed to repetitive trauma or pro...
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