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58 results
  • ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells. [Review]
    Biol Blood Marrow Transplant 2019; 25(4):625-638Lee DW, Santomasso BD, … Neelapu SS
  • Chimeric antigen receptor (CAR) T cell therapy is rapidly emerging as one of the most promising therapies for hematologic malignancies. Two CAR T products were recently approved in the United States and Europe for the treatment ofpatients up to age 25years with relapsed or refractory B cell acute lymphoblastic leukemia and/or adults with large B cell lymphoma. Many more CAR T products, as well as…
  • Methods and role of minimal residual disease after stem cell transplantation. [Journal Article]
    Bone Marrow Transplant 2019; 54(5):681-690Ladetto M, Böttcher S, … Bader P
  • Relapse is the major cause of treatment failure after stem cell transplantation. Despite the fact that relapses occurred even if transplantation was performed in complete remission, it is obvious that minimal residual disease is present though not morphologically evident. Since adaptive immunotherapy by donor lymphocyte infusion or other novel cell therapies as well as less toxic drugs, which can…
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