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4,852 results
  • Drugs and Lactation Database (LactMed): Zidovudine [BOOK]
    Drugs and Lactation Database (LactMed). National Library of Medicine (US): Bethesda (MD)BOOK
  • Zidovudine has been well studied during breastfeeding. Milk levels are low and most breastfed infants do not have detectable blood levels. Some breastfed infants have developed anemia during maternal therapy.
  • The Use of Zidovudine Pharmacophore in Multi-Target-Directed Ligands for AIDS Therapy. [Review]
    Molecules. 2022 Dec 03; 27(23)Bianco MDCAD, Inacio Leite D, … Bastos MM
  • The concept of polypharmacology embraces multiple drugs combined in a therapeutic regimen (drug combination or cocktail), fixed dose combinations (FDCs), and a single drug that binds to different targets (multi-target drug). A polypharmacology approach is widely applied in the treatment of acquired immunodeficiency syndrome (AIDS), providing life-saving therapies for millions of people living wit…
  • Participation of inpatients in multidisciplinary team meetings: An explorative study of mental healthcare workers' perception. [Multicenter Study]
    Arch Psychiatr Nurs. 2022 12; 41:277-285.Berben K, Dierckx E, … Verhaeghe S
  • CONCLUSIONS: Mental healthcare workers report a great willingness to involve inpatients in MTMs. However, social workers, nurses, and pedagogues feel less competent and are less positive about the effects of patient participation in MTMs. Mental healthcare workers with recent training in patient participation and experience in patient participation in MTMs feel more competent and believe more often that the patient should fulfil a more autonomous role when participating in a MTM. These results can be used to understand and improve patient participation in MTMs in mental healthcare.
  • In Situ Super-Resolution Imaging of Telomeres with DNA-PAINT. [Journal Article]
    ACS Omega. 2022 Nov 08; 7(44):40512-40519.Liu Y, Ye X, … Cui Y
  • Telomeres are located at the ends of chromosomes and play an important role in maintaining the integrity of chromosomes and controlling the cycle of cell division. Studies have shown that abnormal telomere length may lead to the occurrence of some diseases. Therefore, accurate measurement of telomere length will be helpful for the prediction and diagnosis of related diseases. DNA point accumulati…
  • [Adverse cardiovascular effects of antiretrovirals in female mice during gestation]. [Journal Article]
    Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2022 Sep; 38(3):252-257.Yu HJ, Chen ZS, … Fang QJ
  • Objective: To evaluate the effects of antiretrovirals on cardiovascular function and some biochemical indexes in gestational female rats. Methods: Nineteen 9-week-old female and six 10-week-old male SD rats were divided into normal control group (CON) and highly active antiretroviral therapy group (HARRT), 9/10 female rats and 3 male rats were combined into one cage, totally 2 cages. Female rats …
  • Highly Sensitive Electrochemical Detection of Azithromycin with Graphene-Modified Electrode. [Journal Article]
    Sensors (Basel). 2022 Aug 18; 22(16)Pogăcean F, Varodi C, … Pruneanu S
  • An electrochemical cell containing two graphite rods was filled with the appropriate electrolyte (0.2 M ammonia + 0.2 M ammonium sulphate) and connected to the exfoliation system to synthesize graphene (EGr). A bias of 7 V was applied between the anode and cathode for 3 h. After synthesis, the morphology and structure of the sample was characterized by SEM, XRD, and FTIR techniques. The material …
  • Chronic Kidney Disease in a Large National Human Immunodeficiency Virus Treatment Program. [Journal Article]
    Healthcare (Basel). 2022 Aug 08; 10(8)Paengsai N, Noppakun K, … Kosachunhanun N
  • Tenofovir disoproxil fumarate (TDF) is associated with a risk of chronic kidney disease (CKD), especially in Asian populations. Data from the Thai national health insurance system was used to assess CKD incidence in patients receiving antiretroviral therapy in real-world practice. We analyzed data from patients who initiated one of the following first-line regimens: zidovudine + lamivudine + nevi…
  • Can plant-derived anti-HIV compounds be used in COVID-19 cases? [Journal Article]
    Med Hypotheses. 2022 Sep; 166:110926.Das D, Bihari Jena A, … Pathak S
  • People living with HIV are more exposed to the adverse health effects of the worldwide COVID-19 pandemic. The pandemic's health and social repercussions may promote drug abuse and inadequate HIV management among this demographic. The coronavirus pandemic of 2019 (COVID-19) has caused unprecedented disruption worldwide in people's lives and health care. When the COVID-19 epidemic was identified, p…
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