- Obstetric outcomes of twin pregnancies at advanced maternal age: A retrospective study. [Journal Article]
- TJTaiwan J Obstet Gynecol 2018; 57(1):64-67
- CONCLUSIONS: In twin pregnancies, advanced maternal age experienced significant higher risk of postpartum hemorrhage, gestational diabetes and premature delivery. Neither adverse neonatal outcomes nor stillbirth was significantly associated with maternal age.
- Role of granulocyte colony-stimulating factor in human reproduction. [Review]
- JRJ Res Med Sci 2018; 23:7
- As new research reveals, granulocyte colony-stimulating factor (G-CSF) plays an effective role in pregnancy success, considering that it not only affects the embryo implantation and ovarian function ...
As new research reveals, granulocyte colony-stimulating factor (G-CSF) plays an effective role in pregnancy success, considering that it not only affects the embryo implantation and ovarian function but also it promotes endometrial thickening and improves the pathophysiology of endometriosis, which all fundamentally lead to reducing pregnancy loss. In this review, we focus on the role of G-CSF in human reproduction. We summarized its role in ovulation, luteinized unruptured follicle syndrome, poor responders, improving repeatedin vitrofertilization failure, endometrial receptivity and treatment of thin endometrium, and recurrent spontaneous abortion.
- Management of Skull Base Tumors in the Obstetric Population: a Case Series. [Journal Article]
- WNWorld Neurosurg 2018 Feb 14
- CONCLUSIONS: Management of a symptomatic tumor during pregnancy requires balancing the potential to cure the mother and to harm the fetus. Trimester of pregnancy is the most critical factor in evaluating the need for urgent management. Surgery during the second trimester is the optimal time, as it is associated with the least risk for spontaneous abortion or preterm birth. The first and third trimesters are associated with increased risk of miscarriage and preterm labor respectively. Induction of labor for preterm delivery, followed by surgery, may be appropriate in early third trimester. Nonetheless, any pregnant woman with an emergent presentation should be offered surgery, regardless of trimester.
- Fetoplacental malformations and abnormalities. A retrospective analysis of 398 cases. [Journal Article]
- TMTunis Med 2017; 95(3):201-205
- CONCLUSIONS: An efficient fetopathological examination should be as complete as possible, including examination of placenta. Everything must be integrated into a data collection and complete clinical information.
- A seroprevalence and relationship survey of brucellosis between pregnant women and women with spontaneous abortion in Iran. [Journal Article]
- MJMed J Islam Repub Iran 2017; 31:42
- Background: Brucellosis is one of the most prevalent diseases common between humans and animals. It is also called Malta fever, Undulant fever and Mediterranean fever. This diseas...
Background: Brucellosis is one of the most prevalent diseases common between humans and animals. It is also called Malta fever, Undulant fever and Mediterranean fever. This disease is spread by consuming milk and its unpasteurized derivatives. Clinical symptoms of brucellosis in humans are fever, chills, headache, muscular pain, tiredness, loss of appetite, joint pain, weight loss, constipation, sore throat, and dry cough. The present study aimed at surveying the seroprevalence of brucellosis in pregnant women and those women who suffered from spontaneous abortion.Methods:This case- control study was conducted in Sanandaj (Iran) in 2016 and included 2 groups of pregnant women: one group included 160 pregnant women and the other included 160 women who suffered from spontaneous abortion. Then, the participants were asked to fill out the questionnaire. After receiving permission from an obstetrician, a 10-cc blood sample was taken from each person to be used in the Rose Bengal, Wright, 2ME, and Coombs tests. Independent samples t test and Chi-square test were used to analyze the data and compare the groups.Results:Mean±SD age of women in the case group was 30.9±7.3 years, while it was 27.74±5.41 years in control women. The Rose Bengal, Wright, and 2ME prevalence for both groups was negative, but the Coombs and Wright tests score was 33 (20.6%) in pregnant women and it was 27 (16.9%) in women who experienced spontaneous abortion. No meaningful relationship was observed between spontaneous abortion and brucellosis (p= 0.39).Conclusion:Even though the present study did not find a meaningful relationship between spontaneous abortion and brucellosis (p=0.39), high brucella seroprevalence rates between both groups of women indicated that screening tests should be considered before gestation as an appropriate therapeutic strategy.
- Severity and management of postabortion complications among women in Zimbabwe, 2016: a cross-sectional study. [Journal Article]
- BOBMJ Open 2018 02 10; 8(2):e019658
- CONCLUSIONS: Zimbabwean women experience considerable abortion-related morbidity, particularly young, rural or less educated women. Abortion-related morbidity and concomitant mortality could be reduced in Zimbabwe by liberalising the abortion law, providing PAC in primary health centres, and training nurses to use medical evacuation with misoprostol and MVA. Regular in-service training on PAC guidelines with follow-up audits are needed to ensure compliance and availability of equipment, supplies and trained staff.
- Trajectory of vitamin D status during pregnancy in relation to neonatal birth size and fetal survival: a prospective cohort study. [Journal Article]
- BPBMC Pregnancy Childbirth 2018 Feb 13; 18(1):51
- CONCLUSIONS: Vitamin D deficiency in late pregnancy was associated with higher odds of SGA and LBW. Lower 25OHD in early pregnancy was only associated with pregnancy loss. Vitamin D status trajectory from early to late pregnancy was inversely associated with SGA, LBW and preterm delivery with the lowest odds among women with the highest increment in 25OHD. Thus, both higher vitamin D status in late pregnancy and gestational vitamin D status trajectory can be suspected to play a role in healthy pregnancy.
- Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: I: Fetal risks. [Journal Article]
- NeurNeurology 2018 Feb 07
- CONCLUSIONS: Our results showed that natalizumab exposure to up 12 weeks of gestation is associated with an increased risk of SA, although within the limits expected in the general population, whereas the risk of CA needs further investigation. Taking into account the high risk of disease reactivation after natalizumab suspension, pregnancy could be planned continuing natalizumab while strictly monitoring conception.
- The Status of Genetic Screening in Recurrent Pregnancy Loss. [Review]
- OGObstet Gynecol Clin North Am 2018; 45(1):143-154
- Recurrent pregnancy loss is often idiopathic, but numerical and structural chromosomal abnormalities constitute an important cause. Numerical chromosomal abnormalities in the conceptus are primarily ...
Recurrent pregnancy loss is often idiopathic, but numerical and structural chromosomal abnormalities constitute an important cause. Numerical chromosomal abnormalities in the conceptus are primarily due to meiotic nondisjunction; the rate and complexity of embryonic aneuploidy are driven by female age. Structural chromosomal abnormalities (balanced translocations or inversions) can lead to unbalanced gametes depending on specific recombination and segregation patterns during meiosis. The attendant reproductive risk depends on the type of rearrangement and its parental origin. Current methods for analysis of products of conception include cytogenetics, array comparative genomic hybridization, and single nucleotide polymorphism microarray; each platform has advantages and disadvantages.
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- Use of trimethoprim-sulfamethoxazole during pregnancy and risk of spontaneous abortion: a nested case control study. [Journal Article]
- BJBr J Clin Pharmacol 2018 Feb 08
- CONCLUSIONS: Given that this drug is widely use in HIV patients to prevent opportunistic infections and malaria, there is an urgent need to identify potential data sources in Africa for analysis of early pregnancy exposure to TMP-SMX.