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3,764 results
  • Identifying Familial Hypercholesterolemia Using a Blood Donor Screening Program With More Than 1 Million Volunteer Donors. [Journal Article]
  • JCJAMA Cardiol 2019 May 22
  • Jackson CL, Keeton JZ, … Khera A
  • CONCLUSIONS: The prevalence of familial hypercholesterolemia using the Make Early Diagnosis to Prevent Early Death criteria in a large cohort of blood donors was similar to the estimated prevalence of this disorder in the general population. The blood donor screening program could be a novel strategy to detect and notify individuals with potential familial hypercholesterolemia, particularly younger individuals in whom early detection and treatment is especially helpful, as well as guide cascade screening.
  • Myosteatosis is associated with poor physical fitness in patients undergoing hepatopancreatobiliary surgery. [Journal Article]
  • JCJ Cachexia Sarcopenia Muscle 2019 May 21
  • West MA, van Dijk DPJ, … Olde Damink SWM
  • CONCLUSIONS: There is a positive association between preoperative CT SM-RA and preoperative physical fitness (V ̇ O2 at AT and at peak). This study demonstrates that myosteatosis, and not sarcopenia, is associated with reduced aerobic physical fitness. Combining both myosteatosis and physical fitness variables may provide additive risk stratification accuracy and guide interventions during the perioperative period.
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