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88 results
  • Anti-HIV activity of southern African plants: Current developments, phytochemistry and future research. [Review]
  • JEJ Ethnopharmacol 2018 Jan 10; 210:133-155
  • Prinsloo G, Marokane CK, Street RA
  • CONCLUSIONS: An investigation of the plants from southern Africa with ethnobotanical use for the treatment of HIV, management of HIV or HIV-related symptoms, therefore provide a very good analysis of the major assays employed and the anti-viral compounds and compound groups identified. The similarity in identified anti-viral compounds worldwide should support the progression from in vitro studies to in vivo testing in development of affordable and effective anti-HIV agents for countries with high infection and mortality rates due to HIV/AIDS.
  • Rational Vehicle Design Ensures Targeted Cutaneous Steroid Delivery. [Journal Article]
  • JCJ Clin Aesthet Dermatol 2017; 10(2):12-19
  • Kircik L, Okumu F, … Sugarman J
  • CONCLUSIONS: Formulation-6/DFD-01 had the optimal balance of betamethasone retention in the skin, with low systemic absorption. This designed vehicle ensured retention of the corticosteroid in skin layers to maximize local efficacy while minimizing potential for hypothalamic-pituitary-adrenal suppression.
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