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(Accupril)
845 results
  • StatPearls: Quinapril [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)TandanNitinNSouthern Illinois University School of MedicineCassagnolManouchkatheMSt. John's UniversityBOOK
  • Quinapril is a medication utilized in managing hypertension, which is a significant risk factor for coronary heart disease. This activity reviews the indications, mechanism of action, administration, adverse events, contraindications, monitoring, and toxicity. This article aims to highlight pertinent points regarding quinapril as needed by interprofessional teams managing patients with hypertensi…
  • Binder jetting 3D printing of challenging medicines: From low dose tablets to hydrophobic molecules. [Journal Article]
    Eur J Pharm Biopharm. 2022 Jan; 170:144-159.Kozakiewicz-Latała M, Nartowski KP, … Karolewicz B
  • Increasing access to additive manufacturing technologies utilising easily available desktop devices opened novel ways for formulation of personalized medicines. It is, however, challenging to propose a flexible and robust formulation platform which can be used for fabrication of tailored solid dosage forms composed of APIs with different properties (e.g., hydrophobicity) without extensive optimiz…
  • Pulmonary adverse drug event data in hypertension with implications on COVID-19 morbidity. [Journal Article]
    Sci Rep. 2021 06 25; 11(1):13349.Jaberi-Douraki M, Meyer E, … Xu X
  • Hypertension is a recognized comorbidity for COVID-19. The association of antihypertensive medications with outcomes in patients with hypertension is not fully described. However, angiotensin-converting enzyme 2 (ACE2), responsible for host entry of the novel coronavirus (SARS-CoV-2) leading to COVID-19, is postulated to be upregulated in patients taking angiotensin-converting enzyme inhibitors (…
  • Experimental autoimmune myocarditis in rats and therapeutic histamine H1 - H4 receptor inhibition. [Journal Article]
    J Physiol Pharmacol. 2018 Dec; 69(6)Stasiak A, Gola J, … Fogel WA
  • Myocarditis, a life threatening disease, is still not adequately treated. Histamine plays an important role in physiology and pathophysiology of cardiovascular system. All four histamine receptors (H1R - H4R), are present in the heart. Experimental autoimmune myocarditis (EAM) was used to investigate which histamine receptor had a greater impact on the disease's progression. EAM was evoked in Lew…
  • Drugs and Lactation Database (LactMed): Quinapril [BOOK]
    Drugs and Lactation Database (LactMed). National Library of Medicine (US): Bethesda (MD)BOOK
  • Because of the low levels of quinapril in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury: Angiotensin-Converting Enzyme Inhibitors [BOOK]
    LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases: Bethesda (MD)BOOK
  • The angiotensin-converting enzyme (ACE) inhibitors are a widely used class of antihypertensive medications that act by blocking the conversion of angiotensin I to angiotensin II, thus inhibiting an intermediate step in the renin-angiotensin pathway. The ACE inhibitors are rare causes of clinically apparent liver injury. The ACE inhibitors act by blocking the conversion of angiotensin I to angiote…
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury: Quinapril [BOOK]
    LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases: Bethesda (MD)BOOK
  • Quinapril is an angiotensin-converting enzyme (ACE) inhibitor used in the therapy of hypertension and congestive heart failure. Quinapril is associated with a low rate of transient serum aminotransferase elevations, but has yet to be linked to instances of acute liver injury.
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