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5,133 results
  • Efficacy of Topical Treatments for the Management of Symptomatic Oral Lichen Planus: A Systematic Review. [Review]
    Int J Environ Res Public Health. 2023 Jan 10; 20(2)Serafini G, De Biase A, … Lollobrigida M
  • Oral lichen planus (OLP) is a chronic mucosal inflammatory disease associated with T-cell-mediated immunological dysfunction. Symptomatic OLP is a painful condition, and complete healing is often not achieved. The aim of this systematic review was to assess the effectiveness of topical drugs, medications, and other interventions compared to placebo or to other treatments in pain reduction and cli…
  • Therapeutic inertia during isotretinoin treatment of juvenile acne by dermatologists, paediatricians and general practitioners. [Journal Article]
    Ann Dermatol Venereol. 2023 Jan 13 [Online ahead of print]Mahé E, Werner A, … Groupe de Recherche de la Société Française de Dermatologie Pédiatrique, Association Française de Pédiatrie Ambulatoire
  • CONCLUSIONS: Concerns over the psychiatric consequences of isotretinoin in adolescents, the need for frequent follow-up, and lack of continuing medical education were identified as factors favouring inertia in the initiation of isotretinoin treatment in patients with moderate-to-very severe juvenile acne, particularly among paediatricians and GPs. Potential strategies to overcome these barriers include regular training, simplified recommendations in French, and access to first-time prescription for paediatricians and GPs.
  • Vulvar sebaceous hyperplasia - a problematic dermatosis of the vulva. [Journal Article]
    Ginekol Pol. 2023 Jan 04 [Online ahead of print]Gorski K, Korczynska L, … Ciebiera M
  • Sebaceous glandular hyperplasia (SGH) is a benign form of skin pathology, occurring in approximately one percent of the population. Risk factors for the SGH include advanced age, male sex, exposure to UV radiation and immunosuppression. The pathogenesis of SGH involves hormonal changes, is also regulated by insulin levels, thyroid stimulating hormone (TSH) and cortisol. SGH manifests itself as so…
  • Clinical practice Guidelines for 5-Aminolevulinic acid photodynamic therapy for acne vulgaris in China. [Review]
    Photodiagnosis Photodyn Ther. 2022 Dec 30; 41:103261.Wang P, Wang B, … Wang X
  • A variety of evidence suggest that 5-Aminolevulinic acid-based photodynamic therapy (ALA-PDT) is clinically effective in management of acne vulgaris. Several clinical guidelines for acne recommend PDT as an alternative treatment modality for severe acne. However, there is a lack of detailed clinical guideline for PDT in acne treatment. To propose up-to-date, evidence-based and practical recommend…
  • Isotretinoin, Vitamin A Supplements, and Unintended Pregnancies in Post Roe v. Wade America. [Editorial]
    Cureus. 2022 Nov; 14(11):e31442.Paidisetty PS, Wang LK, … Nawas ZY
  • Isotretinoin is a potent vitamin A derivative that is used to treat acne. However, despite its utility in dermatologic care, it is also highly teratogenic and can cause severe life-threatening fetal abnormalities in the first trimester of pregnancy. As a result, existing regulations are stringent in order to prevent accidental pregnancies in women taking isotretinoin. In the unlikely case of an u…
  • Reactive perforating collagenosis and systemic lupus erythematosus: A rare case report. [Case Reports]
    Medicine (Baltimore). 2022 Dec 02; 101(48):e32138.Alenzi F
  • CONCLUSIONS: Variable skin rash can mimic systemic lupus erythematosus and vasculitis. Therefore, reactive perforating collagenosis is a skin condition that requires high clinical suspension for diagnosis, and it might be challenging to determine whether it is an association or a complication. Furthermore, the timing of the skin biopsy may be crucial for the diagnosis of reactive perforating collagenosis.
  • Chronic Osteomyelitis of the Cranial Vault in an Adolescent Female: A Case Report. [Case Reports]
    NMC Case Rep J. 2022; 9:383-388.Ujihara M, Kobayashi M, … Fujimaki T
  • We report an 18-year-old female patient who developed left temporal headache and fever one month after administration of isotretinoin for acne. Imaging studies demonstrated osteolytic change in the left frontal bone, and the lesion showed gadolinium contrast enhancement. Biopsy confirmed the diagnosis of osteomyelitis, and the symptoms improved after 8 months of medication with antibiotics and no…
  • Porokeratosis ptychotropica: a case report. [Case Reports]
    J Yeungnam Med Sci. 2022 Dec 05 [Online ahead of print]Ryoo YW, Kim Y, … Kim SA
  • Porokeratosis ptychotropica is an uncommon form of porokeratosis, which was initially described in 1995. It is clinically characterized by symmetrical reddish to brown-colored hyperkeratotic, verrucous, or psoriasiform plaques on the perianal and gluteal regions. The lesions tend to integrate and expand centrally, with small peripheral satellite lesions. Early skin biopsy and appropriate diagnosi…
  • [Translated article] Oral Supplementation and Systemic Drugs for Skin Aging: A Narrative Review. [Review]
    Actas Dermosifiliogr. 2022 Dec 01 [Online ahead of print]Morgado-Carrasco D, Gil-Lianes J, … Piquero-Casals J
  • Skin aging is influenced by intrinsic and extrinsic factors and involves multiple pathogenic mechanisms. The most widely used treatments are topical products and minimally invasive procedures. Evidence on the benefits of systemic therapy is limited for several reasons: reliance on mostly small and predominantly female samples, short study durations, methodologic heterogeneity, and a lack of conse…
  • Acneiform Eruption Following Elexacaftor-Tezacaftor-Ivacaftor Treatment in Patients With Cystic Fibrosis. [Journal Article]
    JAMA Dermatol. 2023 Jan 01; 159(1):68-72.Okroglic L, Sohier P, … Oulès B
  • CONCLUSIONS: This case series study found that acneiform eruption is an adverse event associated with ELX-TEZ-IVA treatment in patients with cystic fibrosis. Most patients developed mild lesions. However, isotretinoin treatment may be necessary in some patients. The mechanism of ELX-TEZ-IVA-associated acneiform eruption is currently unknown, but the observation of necrotizing infundibular crystalline folliculitis in biopsied patients may guide further exploration.
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