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(Acne topical antibiotics for)
1,283 results
  • Essential Oils in the Treatment of Various Types of Acne-A Review. [Review]
    Plants (Basel). 2022 Dec 24; 12(1)Nurzyńska-Wierdak R, Pietrasik D, Walasek-Janusz M
  • Acne is a chronic, common disease that poses a significant therapeutic, psychological and social problem. The etiopathogenesis of this disease is not fully understood. Drugs used in general and external therapy should have anti-seborrhoeic, anticomadogenic, bactericidal, bacteriostatic, and anti-inflammatory properties. Acne treatment is often associated with the long-term use of antibiotics, con…
  • Sixty Years of Benzoyl Peroxide Use in Dermatology. [Journal Article]
    J Drugs Dermatol. 2023 Jan 01; 22(1):54-59.Baldwin H, Elewski B, … Harper J
  • Benzoyl peroxide (BPO) has been used extensively in industry and health care for more than a century and has been approved for the treatment of acne for over 60 years. Recently, BPO received a second approved indication by the US Food and Drug Administration (FDA) for the treatment of rosacea. Topical BPO use has historically been limited by tolerability, photosensitivity, oxidation, and, uncommo…
  • Formulation and Characterization of Oleogel as a Topical Carrier of Azithromycin. [Journal Article]
    AAPS PharmSciTech. 2022 Dec 15; 24(1):17.Al-Saedi ZHF, Salih ZT, … Jasim SA
  • This study aims to formulate azithromycin oleogel to locally treat skin infections such as acne vulgaris and skin wound infection. Providing a form of azithromycin that can be administered topically is highly desired to prevent unwanted systemic complications including diarrhea, nausea, and abdominal pain. Additionally, it will avoid first pass metabolism, improves patient acceptance, provides an…
  • Clinical characteristics and treatment outcomes of Pityrosporum folliculitis in immunocompetent patients. [Review]
    Arch Dermatol Res. 2022 Dec 14 [Online ahead of print]Green M, Feschuk AM, … Maibach HI
  • Pityrosporum folliculitis (PF) is a fungal acneiform disease of the hair follicles that often presents with pruritic papules and pustules on the upper body and face. This condition is commonly mistaken for acne vulgaris and can be distinguished from bacterial acne by the presence of fungal spores in the follicular lumen. Although studies have been performed to describe PF in cohorts, little work …
  • Acneiform Eruption Following Elexacaftor-Tezacaftor-Ivacaftor Treatment in Patients With Cystic Fibrosis. [Journal Article]
    JAMA Dermatol. 2023 Jan 01; 159(1):68-72.Okroglic L, Sohier P, … Oulès B
  • CONCLUSIONS: This case series study found that acneiform eruption is an adverse event associated with ELX-TEZ-IVA treatment in patients with cystic fibrosis. Most patients developed mild lesions. However, isotretinoin treatment may be necessary in some patients. The mechanism of ELX-TEZ-IVA-associated acneiform eruption is currently unknown, but the observation of necrotizing infundibular crystalline folliculitis in biopsied patients may guide further exploration.
  • Novel and emerging treatment options for acne vulgaris [Review]
    Eur J Dermatol. 2022 07 01; 32(4):451-458.Auffret N, Claudel JP, … Dreno B
  • The principal actors in acne are the sebaceous gland, keratinocytes of the follicle and skin microbiome/innate immunity. Current acne treatments are frequently accompanied by side effects or may cause antibacterial resistance. New formulations and emerging treatments with novel mechanisms of action and improved formulations have recently been made available or are currently under development. Thi…
  • Acne care in health care providers during the COVID-19 pandemic: A national survey. [Journal Article]
    Dermatol Ther. 2022 10; 35(10):e15753.Cretu S, Dascalu M, Salavastru CM
  • The medical face mask, widely used by health care providers (HCPs) during the COVID-19 pandemic, is reported to be associated with adverse reactions, among which acne is one of the most common. This study aims to evaluate treatment strategies employed by HCPs affected by acne in association with prolonged medical face mask use, their openness towards accessing telemedicine as a patient, and other…
  • Hydrogels for localized drug delivery: A special emphasis on dermatologic applications. [Review]
    Dermatol Ther. 2022 11; 35(11):e15830.Jindal S, Awasthi R, … Kulkarni GT
  • Skin disease treatment is a complex and time-consuming process due to the complex etiology, numerous side effects of conventional therapies, and difficulties in determining primary causes of the disease. Superficial wounds are often easy to treat. However, treatment of severe wounds caused by burn is challenging for clinicians. Optimum therapeutic benefits are based on the site-specific delivery …
  • Montelukast as an effective adjuvant in the treatment of moderate acne vulgaris. [Randomized Controlled Trial]
    Dermatol Ther. 2022 10; 35(10):e15770.Fazelzadeh Haghighi N, Dastgheib L, … Ranjbar S
  • Although antibiotics are among the most commonly used treatments of acne, there are refractory cases, or they can cause some complications. Recently, leukotriene B4 has been found to play a major role in inflammatory acne lesions. This double blind, randomized clinical trial was conducted on 108 patients with acne who needed systemic therapy and referred to dermatology clinics affiliated to Shira…
  • Emerging drugs for the treatment of acne: a review of phase 2 & 3 trials. [Review]
    Expert Opin Emerg Drugs. 2022 09; 27(3):241-261.Bhatt S, Kothari R, … Goldust M
  • Acne vulgaris is one of the commonest dermatoses encountered in a dermatology clinic. Although the inflammatory processes are centered around the pilosebaceous unit, a myriad of external factors that alter the pathogenesis have been hypothesized. Newer therapies are focused on targeting these as possible scaffolds for drug development. Existing topical and oral medications have considerable overl…
  • Antibiotic use and bacterial resistance in patients with acne vulgaris. [Review]
    JAAPA. 2022 Aug 01; 35(8):34-39.Bowman S, Sadowski CK
  • Acne vulgaris is a prevalent chronic skin disease caused by obstruction and/or inflammation of pilosebaceous follicles. Each year, about 50 million people in the United States are affected. The use of topical and oral antibiotics to manage acne has been associated with the development of bacterial resistance. This article reviews concerns about antimicrobial use, current treatment recommendations…
  • Acne treatment review and future perspectives. [Review]
    Dermatol Ther. 2022 09; 35(9):e15719.Mohsin N, Hernandez LE, … Nouri K
  • Acne affects approximately 9% of people worldwide and is the most common skin condition in the USA. There are abundant topical and oral treatment options available for patients with acne. First-line agents include topical retinoids, azelaic acid, benzoyl peroxide, and combinations of these agents. For recalcitrant or more severe acne, oral medications, including oral antibiotics, isotretinoin, or…
  • StatPearls: Hidradenitis Suppurativa [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)BallardKimberlyKShumanVictoria L.VLWV Sch Osteo MedicineBOOK
  • Hidradenitis suppurativa (HS), also called acne inversus, is a chronic inflammatory skin condition with lesions including deep-seated nodules and abscesses, draining tracts, and fibrotic scars. These lesions most commonly occur in intertriginous areas and areas rich in apocrine glands. Among the most common are axillary, groin, perianal, perineal, and inframammary locations. Treatment varies base…
  • A systematic review and network meta-analysis of topical pharmacological, oral pharmacological, physical and combined treatments for acne vulgaris. [Review]
    Br J Dermatol. 2022 11; 187(5):639-649.Mavranezouli I, Daly CH, … Healy E
  • CONCLUSIONS: Topical pharmacological treatment combinations, chemical peels and photochemical therapy were most effective for mild-to-moderate acne. Topical pharmacological treatment combinations, oral antibiotics combined with topical pharmacological treatments, oral isotretinoin and photodynamic therapy were most effective for moderate-to-severe acne. Further research is warranted for chemical peels, photochemical therapy and photodynamic therapy for which evidence was more limited. What is already known about this topic? Acne vulgaris is the eighth most common disease globally. Several topical, oral, physical and combined treatments for acne vulgaris exist. Network meta-analysis (NMA) synthesizes direct and indirect evidence and allows simultaneous inference for all treatments forming an evidence network. Previous NMAs have assessed a limited range of treatments for acne vulgaris and have not evaluated effectiveness of treatments for moderate-to-severe acne. What does this study add? For mild-to-moderate acne, topical treatment combinations, chemical peels, and photochemical therapy (combined blue/red light; blue light) are most effective. For moderate-to-severe acne, topical treatment combinations, oral antibiotics combined with topical treatments, oral isotretinoin and photodynamic therapy (light therapy enhanced by a photosensitizing chemical) are most effective. Based on these findings, along with further clinical and cost-effectiveness considerations, National Institute for Health and Care Excellence (NICE) guidance recommends, as first-line treatments, fixed topical treatment combinations for mild-to-moderate acne and fixed topical treatment combinations, or oral tetracyclines combined with topical treatments, for moderate-to-severe acne.
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